S(-)-VERAPAMIL

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Company Name: J & K SCIENTIFIC LTD.  
Tel: 18210857532 18210857532
Email: jkinfo@jkchemical.com
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 18930552037
Email: 3bsc@sina.com
Company Name: Chemsky（shanghai）International Co.,Ltd.  
Tel: 021-50135380
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Company Name: Daicel Chiral Technologies (China)CO.,LTD  
Tel: 021-50460086-9 15921403865
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Company Name: ShangHai Caerulum Pharma Discovery Co., Ltd.  
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Email: sales-cpd@caerulumpharma.com

S(-)-VERAPAMIL manufacturers
S(-)-VERAPAMIL Basic information
Product Name:S(-)-VERAPAMIL
Synonyms:S(-)-VERAPAMIL;S(-)-VERAPAMIL HYDROCHLORIDE;S-Verapamil HCL;[7-cyano-1,7-bis(3,4-dimethoxyphenyl)nonan-3-yl]ammonium chloride;(-)-[3-cyano-3-(3,4-dimethoxyphenyl)hex-6-yl][2-(3,4-dimethoxyphenyl)ethyl]methylammonium chloride;S(-)-VERAPAMIL HYDROCHLORIDE HYDRATE;Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, monohydrochloride, (aS)- (9CI);Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, monohydrochloride, (S)-
CAS:36622-28-3
MF:C27H38N2O4
MW:454.6
EINECS:253-132-8
Product Categories:Calcium Channel Modulators;Verapamil;Voltage-gated Ion Channels;Organics
Mol File:36622-28-3.mol
S(-)-VERAPAMIL Structure
S(-)-VERAPAMIL Chemical Properties
Melting point 131-133 °C
solubility H2O: >30 mg/mL
form solid
color white
Optical Rotation[α]22/D 6.1°, c = 0.1 in ethanol(lit.)
Water Solubility H2O: >30mg/mL
ethanol: soluble
InChIKeyICKXRKHJKXMFLR-LPCSYZHESA-N
SMILESO.Cl.COc1ccc(CCN(C)CCC[C@](C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC
Safety Information
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
Storage Class6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard ClassificationsAcute Tox. 3 Oral
MSDS Information
S(-)-VERAPAMIL Usage And Synthesis
Chemical PropertiesWhite Solid
UsesBoth isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells.
DefinitionChEBI: (S)-verapamil hydrochloride is a hydrochloride salt resulting from the reaction of equimolar amounts of (S)-verapamil and hydrogen chloride. It is an enantiomer of a dexverapamil hydrochloride.
Biochem/physiol ActionsActive enantiomer of (±)-verapamil. Ca2+ channel (L-type) modulator; adrenoceptor antagonist; cardiac depressant.
S(-)-VERAPAMIL Preparation Products And Raw materials
Tag:S(-)-VERAPAMIL(36622-28-3) Related Product Information
R(+)-VERAPAMIL HYDROCHLORIDE,(+)-VERAPAMIL, METHOXY-, HYDROCHLORIDE R(+)-VERAPAMIL HYDROCHLORIDE,(+)-VERAPAMIL, METHOXY-, HYDROCHLORIDE 3,4-Dimethoxy-N-methylphenethylamine hydrochloride Verapamil Impurity O VERAPAMIL RELATED COMPOUND B (50 MG) (AL-PHA-[2-[[2-(3,4-DIMETHOXYPHENYL)-ETHYL]METHYLA-MINO]ETHYL]-3,4-DIMETHOXY-ALPHA-(1-METHY-LETHYL)-BENZENEACETONITRILE MONOHYDROCHLORIDE) Verapamil Impurity N N,N'-Vis[2-(3,4-dimethoxyphenyl)ethyl]-N,N'-dimethyl-1,3-propanediamine dihydrochloride VERAPAMIL RELATED COMPOUND D (50 MG) (5,5'-[[2-(3,4)DIMETHOXYPHENYL)ETHYL]IMINO]BIS[2-(3,4-DIMETHOXYPHENYL)-2-(1-METHYLETHYL)PENTANENI-TRILE] HYDROCHLORIDE) NSC 609249 Verapamil Related Compound A (50 mg) (3,4-Dimethoxy-alpha-[3-(methylamino)propyl]-alpha-(1-methylethyl)-benzeneacetonitrile monohydrochloride) alpha-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-alpha-ethyl-3,4-dimethoxybenzeneacetonitrile monohydrochloride 3-Methyl-2-(3,4-dimethoxyphenyl)butyronitrile N-Methyl-N-(3-chloropropyl)-3,4-dimethoxyphenethylamine (3,4-Dimethoxyphenyl)isopropyl ketone RAC D 617 (N-METHYL-4-(3,4-DIMETHOXYPHENYL)-4-CYANO-5-METHYLHEXYLAMINE) Verapamil Impurity P D 620 Norverapamil hydrochloride