|
|
| | Diethyl-12-bromododecylphosphonate Basic information |
| Product Name: | Diethyl-12-bromododecylphosphonate | | Synonyms: | diethyl 12-bromodecylphosphonate;Phosphonic acid, (12-bromododecyl)-, diethyl ester (9CI);LUN 31289;Phosphonic acid, (12-bromododecyl)-, diethyl ester;Diethyl-12-bromododecylphosphonate | | CAS: | 264231-28-9 | | MF: | C16H34BrO3P | | MW: | 385.32 | | EINECS: | | | Product Categories: | | | Mol File: | 264231-28-9.mol |  |
| | Diethyl-12-bromododecylphosphonate Chemical Properties |
| Boiling point | 429.5±18.0 °C(Predicted) | | density | 1.124±0.06 g/cm3(Predicted) |
| | Diethyl-12-bromododecylphosphonate Usage And Synthesis |
| Description | diethyl 12-bromodecylphosphonate contains bromine and phosphonate moieties. The bromine is a good leaving group and can undergo nucleophilic substitutions. The phosphonate group acts as chelating agent. | | Uses | Diethyl 12-bromododecylphosphonate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | Alkyl-Chain | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Diethyl-12-bromododecylphosphonate Preparation Products And Raw materials |
|