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| | Lexiscan Basic information |
| Product Name: | Lexiscan | | Synonyms: | Cvt 3146;Lexiscan;Regadenoson Hydrate;1-{6-amino-9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-9H-purin-2-yl}-N-methyl-1H-pyrazole-4-carboxamide hydrate | | CAS: | 875148-45-1 | | MF: | C15H18N8O5.H2O | | MW: | 408.37 | | EINECS: | | | Product Categories: | | | Mol File: | 875148-45-1.mol |  |
| | Lexiscan Chemical Properties |
| | Lexiscan Usage And Synthesis |
| Uses | Regadenoson hydrate (NSC 169186) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson hydrate also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS[1][2]. | | References | [1] Trochu JN, et al. Selective A2A adenosine receptor agonist as a coronary vasodilator in conscious dogs: potential for use in myocardial perfusion imaging. J Cardiovasc Pharmacol. 2003 Jan;41(1):132-9. DOI:10.1097/00005344-200301000-00017
[2] Jackson S, et al. The effect of regadenoson-induced transient disruption of the blood-brain barrier on temozolomide delivery to normal rat brain. J Neurooncol. 2016 Feb;126(3):433-9. DOI:10.1007/s11060-015-1998-4 |
| | Lexiscan Preparation Products And Raw materials |
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