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(R)-(+)-Tolvaptan

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(R)-(+)-Tolvaptan manufacturers
(R)-(+)-Tolvaptan Basic information
Product Name:(R)-(+)-Tolvaptan
Synonyms:(R)-(+)-Tolvaptan;Tolvaptan (R)-Isomer;Tolvaptan Impurity R-Isomer;Benzamide, N-[4-[[(5R)-7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl-
CAS:331947-66-1
MF:C26H25ClN2O3
MW:448.94
EINECS:
Product Categories:Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:331947-66-1.mol
(R)-(+)-Tolvaptan Structure
(R)-(+)-Tolvaptan Chemical Properties
Melting point >167°C (dec.)
storage temp. Refrigerator
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
color Off-White
Safety Information
MSDS Information
(R)-(+)-Tolvaptan Usage And Synthesis
UsesAn enantiomer of Tolvaptan. It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
(R)-(+)-Tolvaptan Preparation Products And Raw materials
Tag:(R)-(+)-Tolvaptan(331947-66-1) Related Product Information
5-Dehydro Tolvaptan (S)-(-)-Tolvaptan Benzamide, N-[4-[[(4S,5S)-7-chloro-2,3,4,5-tetrahydro-4,5-dihydroxy-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl- Benzoic acid, 2-methyl-4-[(2-methylbenzoyl)[2-methyl-4-[(2-methylbenzoyl)amino]benzoyl]amino]- Rac-Trans-4-Hydroxy Tolvaptan 5-Chloro-2-[[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester Benzamide, N-[4-[(7-chloro-2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methyl-4-[(2-methylbenzoyl)amino]- N-(4-(7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide Tolvaptan Impurity 3 (DM-4104) Tolvaptan Impurity 65 AJMZAIPORREFDJ-UHFFFAOYSA-N Tolvaptan Impurity 11 N-[4-[[7-Chloro-2,3,4,5-tetrahydro-5-(phosphonooxy)-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methylbenzamide Tolvaptan Impurity 4 (DM-4105) Tolvaptan Impurity 7 3-Chloro-2-methylbenzoyl chloride Tolvaptan Impurity 25 N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methyl-N-(2-methylbenzoyl)-4-[(2-methylbenzoyl)amino]benzamide