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| | (2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL Basic information |
| Product Name: | (2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL | | Synonyms: | 2-S-3-R-plus-4-dimethylamino-1-2-*diphenyl-3-meth;chirald;[S-(R*,S*)]-alpha-[2-(dimethylamino)-1-methylethyl]-alpha-phenylphenethyl alcohol;DEXTROOXYPHENE;chirald tm;D-OXYPHENE;(2S,3R)-4-(DIMETHYLAMINO)-3-METHYL-1,2-DIPHENYLBUTAN-2-OL, TOLUENE SOLUTION;Dextrocarbinol base, (2S,3R)-(+)-4-Dimethylamino-1,2-diphenyl-3-methyl-2-butanol, (2S,3R)-(+)-4-Dimethylamino-3-methyl-1,2-diphenyl-2-butanol | | CAS: | 38345-66-3 | | MF: | C19H25NO | | MW: | 283.41 | | EINECS: | 253-893-6 | | Product Categories: | | | Mol File: | 38345-66-3.mol |  |
| | (2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL Chemical Properties |
| | (2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL Usage And Synthesis |
| Uses | Reducing reagent in organic synthesis. | | Purification Methods | Purify the hydrochloride by dissolving 1.5g in 13.5 mL of 5N HCl, heat to boiling and evaporate in a vacuum. Recrystallise the hydrochloride three times from MeOH/EtOAc giving m 189-190o, []D -33.7o (c 1, H2O) {enantiomer has +34.2o}. The hydrochloride in the minimum volume of water is basified with aqueous 5N NaOH and extracted with Et2O. The extract is dried (K2CO3) and evaporated, leaving a residue which is stored in a desiccator over solid KOH as a low melting solid. It can be recovered using these procedures from asymmetric reductions with LAH, and re-used. [Pohland & Sullivan J Am Chem Soc 77 3400 1955, Sullivan et al. J Org Chem 28 2483 1963, Beilstein 13 IV 2221.] |
| | (2S,3R)-(+)-4-DIMETHYLAMINO-1,2-DIPHENYL-3-METHYL-2-BUTANOL Preparation Products And Raw materials |
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