| Company Name: |
BioBioPha Co., Ltd.
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| Tel: |
0871-65217109 13211707573; |
| Email: |
y.liu@mail.biobiopha.com |
| Products Intro: |
Product Name:Neostenine
CAS:477953-07-4
Purity:97.0% Package:5mg Remarks:BBP01148
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| | Neostenine Basic information |
| Product Name: | Neostenine | | Synonyms: | Neostenine;Furo[2,3-h]pyrrolo[3,2,1-jk][1]benzazepin-10(2H)-one, 8-ethyldodecahydro-11-methyl-, (7aR,8R,8aR,11S,11aR,11bS,11cR)- | | CAS: | 477953-07-4 | | MF: | C17H27NO2 | | MW: | 277.4 | | EINECS: | | | Product Categories: | | | Mol File: | 477953-07-4.mol |  |
| | Neostenine Chemical Properties |
| Boiling point | 414.6±45.0 °C(Predicted) | | density | 1.12±0.1 g/cm3(Predicted) | | pka | 9.93±0.60(Predicted) |
| | Neostenine Usage And Synthesis |
| Uses | Neostenine is a stenine-type Stemona alkaloid, with antitussive activity. Neostenine is also a substrate of P-glycoprotein with high absorptive permeability in Caco-2 monolayer model. Neostenine also shows oral activity for intestinal application[1][2]. | | References | [1] Chung HS, et al. Antitussive activity of Stemona alkaloids from Stemona tuberosa. Planta Med. 2003 Oct;69(10):914-20. DOI:10.1055/s-2003-45100
[2] Leung PH, et al. Intestinal absorption of Stemona alkaloids in a Caco-2 cell model. Planta Med. 2006 Feb;72(3):211-6. DOI:10.1055/s-2005-916195 |
| | Neostenine Preparation Products And Raw materials |
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