| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
PE 154 manufacturers
- PE 154
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- $35.00
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2026-07-27
- CAS:1192750-33-6
- Purity: 99.83%
- Supply Ability: 10g
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| Product Name: | PE 154 | | Synonyms: | 4-[[[7-(Diethylamino)-2,4-dioxo-2H-1-benzopyran-3(4H)-ylidene]methyl]amino]-benzeneacetic acid 2-(1,2,3,4-tetrahydro-9-acridinyl)hydrazide;PE 154;2-(1,2,3,4-Tetrahydro-9-acridinyl)hydrazide-4-[[[7-(diethylamino)-2,4-dioxo-2H-1-benzopyran-3(4H)-ylidene]methyl]amino]-benzeneacetic acid;Benzeneacetic acid, 4-[[[7-(diethylamino)-2,4-dioxo-2H-1-benzopyran-3(4H)-ylidene]methyl]amino]-, 2-(1,2,3,4-tetrahydro-9-acridinyl)hydrazide;(E)-2-(4-(((7-(Diethylamino)-2,4-dioxochroman-3-ylidene)methyl)amino)phenyl)-N'-(1,2,3,4-tetrahydroacridin-9-yl)acetohydrazide;2-[4-({[7-(diethylamino)-2,4-dioxo-3,4-dihydro-2H-1-benzopyran-3-ylidene]methyl}amino)phenyl]-N'-(1,2,3,4-tetrahydroacridin-9-yl)acetohydrazide | | CAS: | 1192750-33-6 | | MF: | C35H35N5O4 | | MW: | 589.68 | | EINECS: | | | Product Categories: | | | Mol File: | 1192750-33-6.mol |  |
| | PE 154 Chemical Properties |
| Melting point | 217 °C | | Boiling point | 789.938±60.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.363±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | 2-8°C | | solubility | DMSO: soluble10mg/mL, clear (warmed) | | pka | 12.598±0.20(predicted) | | form | powder | | color | white to light brown |
| | PE 154 Usage And Synthesis |
| Uses | PE 154 is a potent and fluorescent inhibitor of human acetylcholinesterase | | in vivo | PE154 (hippocampus injection; 0.2 μg per mouse; once) can stain the histochemical of cortical βamyloid plaques[2]. | Animal Model: | 13–20-month-old triple-transgenic mice harbouring three mutant genes (APPswe, PS-1 and tauP301L)[2] | | Dosage: | 0.2 μg per mouse | | Administration: | Hippocampus injection; 0.2 μg per mouse; once | | Result: | Showed the histochemical staining of cortical βamyloid plaques in triple-transgenic (TTG) mice. |
| | IC 50 | BChE: 16 nM (IC50); AChE: 280 pM (IC50) |
| | PE 154 Preparation Products And Raw materials |
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