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3-Deoxysappanone B

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Products Intro: Product Name:3-Deoxysappanone B
CAS:113122-54-6
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CAS:113122-54-6
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CAS:113122-54-6
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CAS:113122-54-6
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Products Intro: Product Name:3-Deoxysappanone B
CAS:113122-54-6
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3-Deoxysappanone B Basic information
Product Name:3-Deoxysappanone B
Synonyms:3-deoxyhematoxylin B;3-Deoxysappanone B;3-Deoxysappanone;4H-1-Benzopyran-4-one, 3-[(3,4-dihydroxyphenyl)methyl]-2,3-dihydro-7-hydroxy-, (R)-;4H-1-Benzopyran-4-one, 3-[(3,4-dihydroxyphenyl)methyl]-2,3-dihydro-7-hydroxy-, (3R)-;Deoxysappanone B
CAS:113122-54-6
MF:C16H14O5
MW:286.28
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Mol File:113122-54-6.mol
3-Deoxysappanone B Structure
3-Deoxysappanone B Chemical Properties
Boiling point 587.4±50.0 °C(Predicted)
density 1.450±0.06 g/cm3(Predicted)
pka7.72±0.40(Predicted)
Safety Information
MSDS Information
3-Deoxysappanone B Usage And Synthesis
UsesDeoxysappanone B (3-Deoxysappanone B) is a homoisoflavone compound isolated from Caesalpinia sappan L (Lignum Sappan). Deoxysappanone B has anti-neuroinflammatory and neuroprotective effects and inhibits the production of neuroinflammatory mediators by blocking the IκB kinase (IKK)-NF-κB and p38/ERK MAPK pathways. Deoxysappanone B can be used in disease studies of neuritis and inflammation-related neurological damage[1].
References[1] Ke-Wu Zeng, et al. Deoxysappanone B, a homoisoflavone from the Chinese medicinal plant Caesalpinia sappan L., protects neurons from microglia-mediated inflammatory injuries via inhibition of IκB kinase (IKK)-NF-κB and p38/ERK MAPK pathways. Eur J Pharmacol. 2015 Feb 5;748:18-29. DOI:10.1016/j.ejphar.2014.12.013
3-Deoxysappanone B Preparation Products And Raw materials
Tag:3-Deoxysappanone B(113122-54-6) Related Product Information
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