JWH 073 6-hydroxyindole metabolite

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JWH 073 6-hydroxyindole metabolite Basic information
Product Name:JWH 073 6-hydroxyindole metabolite
Synonyms:JWH 073 6-hydroxyindole metabolite;(1-butyl-6-hydroxyindol-3-yl)-naphthalen-1-ylmethanone;Methanone, (1-butyl-6-hydroxy-1H-indol-3-yl)-1-naphthalenyl-
CAS:1307803-48-0
MF:C23H21NO2
MW:343.42
EINECS:
Product Categories:
Mol File:1307803-48-0.mol
JWH 073 6-hydroxyindole metabolite Structure
JWH 073 6-hydroxyindole metabolite Chemical Properties
solubility DMF: 20 mg/ml; DMSO: 10 mg/ml; Ethanol: 20 mg/ml
form A crystalline solid
Safety Information
MSDS Information
JWH 073 6-hydroxyindole metabolite Usage And Synthesis
DescriptionJWH 073 is a mildly selective agonist of the central cannabinoid (CB1) receptor derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding CB1 and the peripheral cannabinoid (CB2) receptor are 8.9 and 38 nM, respectively for a CB1:CB2 ratio of 0.23. JWH 073 is one of several synthetic cannabinoids which have been included in smoking mixtures. JWH 073 6-hydroxyindole metabolite is expected to be a urinary metabolite of JWH 073 based on the metabolism of the closely-related JWH 015 and JWH 018.
References[1] MIE MIE AUNG . Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding[J]. Drug and alcohol dependence, 2000, 60 2: Pages 133-140. DOI: 10.1016/s0376-8716(99)00152-0
[2] QIANG ZHANG. Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MS[J]. Analytical and Bioanalytical Chemistry, 2006, 386 5: 1345-1355. DOI: 10.1007/s00216-006-0717-6
JWH 073 6-hydroxyindole metabolite Preparation Products And Raw materials
Tag:JWH 073 6-hydroxyindole metabolite(1307803-48-0) Related Product Information
JWH 018 5-hydroxyindole metabolite (6-hydroxy-1-pentylindol-3-yl)-naphthalen-1-ylmethanone (1-butyl-4-hydroxyindol-3-yl)-naphthalen-1-ylmethanone JWH 018 7-hydroxyindole metabolite JWH 073 2-hydroxyindole metabolite