| Company Name: |
Tcichem, Inc. |
| Tel: |
13918644899 |
| Email: |
81587635@qq.com |
- KU-0058948
-
- $1520.00
-
2026-05-21
- CAS:763111-49-5
- Purity:
- Supply Ability: 10g
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| | 1-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]hexahydro-1H-1,4-diazepine Basic information |
| | 1-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]hexahydro-1H-1,4-diazepine Chemical Properties |
| Melting point | >150°C (dec.) | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | color | Pale Yellow to Yellowish Beige |
| | 1-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]hexahydro-1H-1,4-diazepine Usage And Synthesis |
| Uses | KU-0058948 is a poly (ADP-ribose) polymerase (PARP) inhibitor. Studies show that KU-0058948 a potent agonist that activates transfected extracellular signal-regulated kinase 8 (ERK8) in cells. KU-0058948 induces cell cycle arrest and apoptosis of primary myeloid leukemic cells and myeloid leukemic cell lines in vitro | | Uses | KU-0058948 is a poly (ADP-ribose) polymerase (PARP) inhibitor. Studies show that KU-0058948 is a potent agonist that activates transfected extracellular signal-regulated kinase 8 (ERK8) in cells. KU-0058948 induces cell cycle arrest and apoptosis of primary myeloid leukemic cells and myeloid leukemic cell lines in vitro | | IC 50 | PARP-1: 3.4 nM (IC50) |
| | 1-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]hexahydro-1H-1,4-diazepine Preparation Products And Raw materials |
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