1-Piperazinecarboxylic acid, 4-(5-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester

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1-Piperazinecarboxylic acid, 4-(5-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester Basic information
Product Name:1-Piperazinecarboxylic acid, 4-(5-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester
Synonyms:1-Piperazinecarboxylic acid, 4-(5-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester;tert-butyl 4-(5-aminopyridin-3-yl)piperazine-1-carboxylate;1,1-Dimethylethyl 4-(5-amino-3-pyridinyl)-1-piperazinecarboxylate
CAS:1245914-05-9
MF:C14H22N4O2
MW:278.35
EINECS:
Product Categories:
Mol File:1245914-05-9.mol
1-Piperazinecarboxylic acid, 4-(5-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester Structure
1-Piperazinecarboxylic acid, 4-(5-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester Chemical Properties
form Solid
Safety Information
MSDS Information
1-Piperazinecarboxylic acid, 4-(5-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester Usage And Synthesis
Uses1,1-Dimethylethyl 4-(5-amino-3-pyridinyl)-1-piperazinecarboxylate is the impurity of Palbociclib (HY-50767). Palbociclib is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively[1].
References[1] Fry DW, et al. Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts. Mol Cancer Ther. 2004 Nov;3(11):1427-38. PMID:15542782
1-Piperazinecarboxylic acid, 4-(5-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester Preparation Products And Raw materials
Tag:1-Piperazinecarboxylic acid, 4-(5-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester(1245914-05-9) Related Product Information
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