- Ralinepag
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- $48.00
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2026-08-04
- CAS:1187856-49-0
- Purity: 99.79%
- Supply Ability: 10g
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| | Ralinepag Basic information |
| Product Name: | Ralinepag | | Synonyms: | Ralinepag;2-(((1R,4R)-4-((((4-CHLOROPHENYL)(PHENYL)CARBAMOYL)OXY)METHYL)CYCLOHEXYL)METHOXY)ACETIC ACID;APD 811;APD811;APD-811;APD811;APD-811;APD 811;RALINEPAG;Acetic acid, 2-[[trans-4-[[[[(4-chlorophenyl)phenylamino]carbonyl]oxy]methyl]cyclohexyl]methoxy]-;inhibit,APD-811,Ralinepag,Inhibitor,Prostaglandin Receptor,APD 811 | | CAS: | 1187856-49-0 | | MF: | C23H26ClNO5 | | MW: | 431.91 | | EINECS: | | | Product Categories: | | | Mol File: | 1187856-49-0.mol |  |
| | Ralinepag Chemical Properties |
| Boiling point | 609.086±35.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.257±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 15mg/mL; DMF:PBS (pH 7.2) (1:8): 0.11mg/mL; DMSO: 10mg/mL; Ethanol: 10mg/mL | | form | A solid | | pka | 3.504±0.10(predicted) | | color | White to off-white |
| | Ralinepag Usage And Synthesis |
| Uses | Ralinepag, is a potent non-prostanoid prostacyclin receptor agonist, with EC50s of 8.5 nM, 530 nM and 850 nM for human and rat IP receptor and human DP1 receptor, respectively. | | in vivo | Ralinepag (30 mg/kg, p.o.) markedly reduces the monocrotaline (MCT)-induced increase in pulmonary arterial pressure and pulmonary vessel wall thickness in rats[1]. | | IC 50 | hIP: 8.5 nM (EC50); rIP: 530 nM (EC50); hDP1: 850 nM (EC50) |
| | Ralinepag Preparation Products And Raw materials |
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