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BOC Sciences |
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16314854226; +8616314854226 |
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inquiry@bocsci.com |
| Company Name: |
BOC Sciences |
| Tel: |
16314854226 |
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AZ-GHS-22 manufacturers
- AZ-GHS-22
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- $1130.00
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2026-04-22
- CAS:1143020-91-0
- Purity:
- Supply Ability: 10g
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| | AZ-GHS-22 Basic information |
| Product Name: | AZ-GHS-22 | | Synonyms: | AZ-GHS-22;AZGHS22,AZ GHS 22;Benzamide, 2-chloro-N-[[[6-[[3-(4-methyl-1-piperazinyl)propyl]sulfonyl]-2-benzothiazolyl]amino]carbonyl]-5-(4-morpholinyl)-;2-Chloro-N-[[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-morpholin-4-ylbenzamide | | CAS: | 1143020-91-0 | | MF: | C27H33ClN6O5S2 | | MW: | 621.17 | | EINECS: | | | Product Categories: | | | Mol File: | 1143020-91-0.mol |  |
| | AZ-GHS-22 Chemical Properties |
| density | 1.404±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | 0.1 M HCl: 25 mg/ml,DMSO: 50 mg/ml | | form | A solid | | pka | 5.50±0.70(Predicted) |
| | AZ-GHS-22 Usage And Synthesis |
| Uses | AZ-GHS-22 is a potent, non-CNS penetrant GHS-R1a inverse agonist (IC50=0.77 nM)[1]. | | Biological Activity | AZ-GHS-22 is an inverse agonist of the growth hormone secretagogue receptor 1a (GHS-R1a), which is also known as the ghrelin receptor.1 It binds to GHS-R1a with an IC50 value of 0.77 nM. AZ-GHS-22 decreases food intake in mice by 54% in the first two hours after administration of a 100 mg/kg dose. | | References | 1.McCoull, W., Barton, P., Brown, A.J.H., et al.Identification, optimization, and pharmacology of acylurea GHS-R1a inverse agonistsJ. Med. Chem.57(14)6128-6140(2014) |
| | AZ-GHS-22 Preparation Products And Raw materials |
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