(S)-benzyl (6-acrylamido-1-(4-(7-hydroxy-2-oxo-2H-chromene-3-carbonyl)piperazin-1-yl)-1-oxohexan-2-yl)carbamate
| 中文名称 | (S)-benzyl (6-acrylamido-1-(4-(7-hydroxy-2-oxo-2H-chromene-3-carbonyl)piperazin-1-yl)-1-oxohexan-2-yl)carbamate |
|---|---|
| 中文同义词 | 化合物 T29086;化合物 VA5 TG2 INHIBITOR |
| 英文名称 | (S)-benzyl (6-acrylamido-1-(4-(7-hydroxy-2-oxo-2H-chromene-3-carbonyl)piperazin-1-yl)-1-oxohexan-2-yl)carbamate |
| 英文同义词 | (S)-benzyl (6-acrylamido-1-(4-(7-hydroxy-2-oxo-2H-chromene-3-carbonyl)piperazin-1-yl)-1-oxohexan-2-yl)carbamate;151142;VA5 TG2 inhibitor;VA5 TG2 inhibitor,VA-5 TG2 inhibitor;Carbamic acid, N-[(1S)-1-[[4-[(7-hydroxy-2-oxo-2H-1-benzopyran-3-yl)carbonyl]-1-piperazinyl]carbonyl]-5-[(1-oxo-2-propen-1-yl)amino]pentyl]-, phenylmethyl ester |
| CAS号 | 2088001-24-3 |
| 分子式 | C31H34N4O8 |
| 分子量 | 590.62 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 2088001-24-3.mol |
| 结构式 |  |
(S)-benzyl (6-acrylamido-1-(4-(7-hydroxy-2-oxo-2H-chromene-3-carbonyl)piperazin-1-yl)-1-oxohexan-2-yl)carbamate 性质
| 沸点 | 955.8±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.331±0.06 g/cm3(Predicted) |
| 酸度系数(pKa) | 7.68±0.20(Predicted) |
(S)-benzyl (6-acrylamido-1-(4-(7-hydroxy-2-oxo-2H-chromene-3-carbonyl)piperazin-1-yl)-1-oxohexan-2-yl)carbamate 用途与合成方法
VA5 是 BTK 激酶抑制剂。VA5 有潜力用于研究与 BTK 激酶活性相关的疾病。