3,4,5,6-Tetrahydro-2-pyrimidinethiol manufacturers
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| | 3,4,5,6-Tetrahydro-2-pyrimidinethiol Basic information | | Uses |
| Product Name: | 3,4,5,6-Tetrahydro-2-pyrimidinethiol | | Synonyms: | n,n’-trimethylenethiourea;N,N'-Trimethylenethiourea;Perhydropyrimidine-2-thione;tetrahydro-2(1h)-pyrimidinethion;Tetrahydro-2(1H)-pyrimidinethione;Tetrahydropyrimidine-2-thione;Thiourea, N,N'-1,3-propanediyl-;3,4,5,6-tetrahydropyrimidine-2-thiol | | CAS: | 2055-46-1 | | MF: | C4H8N2S | | MW: | 116.18 | | EINECS: | 218-152-3 | | Product Categories: | Building Blocks;Heterocyclic Building Blocks;Pyrimidines | | Mol File: | 2055-46-1.mol |  |
| | 3,4,5,6-Tetrahydro-2-pyrimidinethiol Chemical Properties |
| Melting point | 210-212 °C (lit.) | | Boiling point | 171.6±23.0 °C(Predicted) | | density | 1.095 (estimate) | | refractive index | 1.5000 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | solid | | pka | 14.98±0.20(Predicted) | | color | White to Off-White | | InChI | 1S/C4H8N2S/c7-4-5-2-1-3-6-4/h1-3H2,(H2,5,6,7) | | InChIKey | NVHNGVXBCWYLFA-UHFFFAOYSA-N | | SMILES | S=C1NCCCN1 | | CAS DataBase Reference | 2055-46-1(CAS DataBase Reference) | | EPA Substance Registry System | Propylenethiourea (2055-46-1) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | RTECS | UW5782000 | | TSCA | TSCA listed | | HazardClass | IRRITANT | | HS Code | 29335990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 3,4,5,6-Tetrahydro-2-pyrimidinethiol Usage And Synthesis |
| Uses | Tetrahydropyrimidine-2(1H)-thione is a reactant in the preparation of aryl substituted heterocycles. | | Uses | Tetrahydropyrimidine-2(1H)-thione is a reactant in the preparation of aryl substituted heterocycles. | | Preparation | The preparation of 3,4,5,6-Tetrahydro-2- pyrimidinethiol is as follows:Carbon disulfide (0.2 mol) was added dropwise to a solution of 1,3-diamino propane 1 (0.2 mol) in H2O/EtOH (20 ml), and the temperature was remained constant at 0-5 oC. After the completion of addition, the reaction mixture was refluxed for 12h and then cooled to room temperature. The precipitate was collected by filtration and recrystallized from EtOH to give pure desired compound. |
| | 3,4,5,6-Tetrahydro-2-pyrimidinethiol Preparation Products And Raw materials |
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