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α,ω,-dipropionic acid nonaethylene glycol manufacturers
- Bis-PEG10-acid
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2025-06-07
- CAS:2055023-26-0
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | α,ω,-dipropionic acid nonaethylene glycol Basic information |
| Product Name: | α,ω,-dipropionic acid nonaethylene glycol | | Synonyms: | α,ω,-dipropionic acid nonaethylene glycol;HOOCCH2CH2O-PEG9-CH2CH2COOH;4,7,10,13,16,19,22,25,28,31-Decaoxatetratriacontanedioic acid;Di-Acid-PEG10;HOOCCH2CH2O-PEG9-CH2CH2COOH/4,7,10,13,16,19,22,25,28,31-Decaoxatetratriacontanedioic acid;Bis-PEG10-acid bis-;PA-PEG9-PA;Bis-PEG10-COOH | | CAS: | 2055023-26-0 | | MF: | C24H46O14 | | MW: | 558.61 | | EINECS: | | | Product Categories: | | | Mol File: | 2055023-26-0.mol |  |
| | α,ω,-dipropionic acid nonaethylene glycol Chemical Properties |
| Boiling point | 657.7±55.0 °C(Predicted) | | density | 1.169±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C, sealed storage, away from moisture | | form | Liquid | | pka | 3.97±0.10(Predicted) | | color | Colorless to light yellow |
| | α,ω,-dipropionic acid nonaethylene glycol Usage And Synthesis |
| Description | Bis-PEG10-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | | Uses | Bis-PEG10-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] Zhao Q, et al. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. J Med Chem. 2019 Oct 24;62(20):9281-9298. DOI:10.1021/acs.jmedchem.9b01264 |
| | α,ω,-dipropionic acid nonaethylene glycol Preparation Products And Raw materials |
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