1-(t-Boc-Aminooxy)-3-aminooxy-propane

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1-(t-Boc-Aminooxy)-3-aminooxy-propane Basic information
Product Name:1-(t-Boc-Aminooxy)-3-aminooxy-propane
Synonyms:1-(t-Boc-Aminooxy)-3-aminooxy-propane;Carbamic acid, N-[3-(aminooxy)propoxy]-, 1,1-dimethylethyl ester;BUN 46805
CAS:1352546-80-5
MF:C8H18N2O4
MW:206.24
EINECS:
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Mol File:1352546-80-5.mol
1-(t-Boc-Aminooxy)-3-aminooxy-propane Structure
1-(t-Boc-Aminooxy)-3-aminooxy-propane Chemical Properties
Safety Information
MSDS Information
1-(t-Boc-Aminooxy)-3-aminooxy-propane Usage And Synthesis
Description1-(t-Boc-Aminooxy)-3-aminooxy-propane is a small PEG reagent containing an aminooxy group and a Boc protected aminoxy group. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.
Uses1-(t-Boc-Aminooxy)-3-aminooxy-propane is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50Alkyl/ether
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
1-(t-Boc-Aminooxy)-3-aminooxy-propane Preparation Products And Raw materials
Tag:1-(t-Boc-Aminooxy)-3-aminooxy-propane(1352546-80-5) Related Product Information
O,Oμ-Diaminopropane-1,3-diol dihydrochloride t-Boc-Aminooxy-PEG3-oxyamine 1,3-Bis-aminooxy propane Carbamic acid, (3-aminopropoxy)-, 1,1-dimethylethyl ester (9CI) tert-Butyl N-(3-Aminopropoxy)carbamate Hydrochloride Carbamic acid, [(5-aminopentyl)oxy]-, 1,1-dimethylethyl ester (9CI)