2-Amino-1,3-bis(carboxylethoxy)propane HCl salt manufacturers
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| | 2-Amino-1,3-bis(carboxylethoxy)propane HCl salt Basic information |
| Product Name: | 2-Amino-1,3-bis(carboxylethoxy)propane HCl salt | | Synonyms: | 2-Amino-1,3-bis(carboxylethoxy)propane HCl salt;2-Amino-1,3-bis(carboxylethoxy)propane;Propanoic acid, 3,3'-[(2-amino-1,3-propanediyl)bis(oxy)]bis-;3,3'-[(2-Aminopropane-1,3-diyl)bis(oxy)]dipropanoic Acid Hydrochloride;3,3’-[(2-Aminopropane-1,3-diyl)bis(oxy)]dipropanoic Acid Hydrochloride;2-Amino-1,3-bis(carboxyethoxy)propane;3-[2-amino-3-(2-carboxyethoxy)propoxy]propanoic acid;3,3'-((2-Aminopropane-1,3-diyl)bis(oxy))dipropionic acid | | CAS: | 1020112-73-5 | | MF: | C9H17NO6 | | MW: | 235.23 | | EINECS: | | | Product Categories: | | | Mol File: | 1020112-73-5.mol |  |
| | 2-Amino-1,3-bis(carboxylethoxy)propane HCl salt Chemical Properties |
| Boiling point | 478.1±45.0 °C(Predicted) | | density | 1.284±0.06 g/cm3(Predicted) | | pka | 3.94±0.10(Predicted) |
| | 2-Amino-1,3-bis(carboxylethoxy)propane HCl salt Usage And Synthesis |
| Description | 2-Amino-1,3-bis(carboxylethoxy)propane is a chemical reagent containing an amino group with two terminal carboxylic acids. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | | Uses | 2-Amino-13-bis(carboxylethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | 2-Amino-1,3-bis(carboxylethoxy)propane HCl salt Preparation Products And Raw materials |
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