[2-(3,4-dimethylphenyl)-3-pyrrol-1-yl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-pyrazin-2-ylmethanone

[2-(3,4-dimethylphenyl)-3-pyrrol-1-yl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-pyrazin-2-ylmethanone Suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354; +1-00000000000
Email:	marketing@targetmol.com
Products Intro:	Product Name:VU0529331 CAS:1286725-49-2 Package:1 mg；5 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	InvivoChem
Tel:	+1-708-310-1919 +1-13798911105
Email:	sales@invivochem.cn
Products Intro:	Product Name:VU0529331 CAS:1286725-49-2 Purity:98% Package:5mg Remarks:V3377

Company Name:	Shanghai Chaolan Chemical Technology Center
Tel:	QQ：65489617 13301690235
Email:	Sales@ATKchemical.com
Products Intro:	CAS:1286725-49-2 Purity:98 Package:1G,5G,10G,50G,100G,500G

Company Name:	Fan De(Beijing) Biotechnology Co., Ltd.
Tel:	15911056312
Email:	liming@bio-fount.com
Products Intro:	Product Name:[2-(3,4-dimethylphenyl)-3-pyrrol-1-yl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-pyrazin-2-ylmethanone CAS:1286725-49-2 Purity:97.0% Package:5mg

Company Name:	Beijing Jin Ming Biotechnology Co., Ltd.
Tel:	010-60605840
Email:	psaitong@jm-bio.com
Products Intro:	Product Name:VU0529331 CAS:1286725-49-2 Purity:>=98% Package:1mg

[2-(3,4-dimethylphenyl)-3-pyrrol-1-yl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-pyrazin-2-ylmethanone Basic information

Product Name:	[2-(3,4-dimethylphenyl)-3-pyrrol-1-yl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-pyrazin-2-ylmethanone
Synonyms:	[2-(3,4-dimethylphenyl)-3-pyrrol-1-yl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-pyrazin-2-ylmethanone;VU0529331;Methanone, [2-(3,4-dimethylphenyl)-2,6-dihydro-3-(1H-pyrrol-1-yl)pyrrolo[3,4-c]pyrazol-5(4H)-yl]-2-pyrazinyl-;VU-0529331,VU0529331;(2-(3,4-Dimethylphenyl)-3-(1H-pyrrol-1-yl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl)(pyrazin-2-yl)methanone
CAS:	1286725-49-2
MF:	C22H20N6O
MW:	384.43
EINECS:
Product Categories:
Mol File:	1286725-49-2.mol

[2-(3,4-dimethylphenyl)-3-pyrrol-1-yl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-pyrazin-2-ylmethanone Chemical Properties

Boiling point	631.4±55.0 °C(Predicted)
density	1.34±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : 5 mg/mL (13.01 mM; Need ultrasonic and warming)
form	Solid
pka	-0.07±0.10(Predicted)
color	White to off-white

Safety Information

MSDS Information

[2-(3,4-dimethylphenyl)-3-pyrrol-1-yl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-pyrazin-2-ylmethanone Usage And Synthesis

Uses	VU0529331 is a modestly selective non-GIRK1-containing G protein-gated, inwardly-rectifying, potassium channel (non-GIRK1/X) activator, with EC50s of 5.1 μM and 5.2 μM for GIRK2 and GIRK1/2 in HEK293 cells, respectively, also effective on GIRK4 homomeric channel[1].
References	[1] Kozek KA, et al. Discovery and Characterization of VU0529331, a Synthetic Small-Molecule Activator of Homomeric G Protein-Gated, Inwardly Rectifying, Potassium (GIRK) Channels. ACS Chem Neurosci. 2018 Sep 13. DOI:10.1021/acschemneuro.8b00287

[2-(3,4-dimethylphenyl)-3-pyrrol-1-yl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-pyrazin-2-ylmethanone Preparation Products And Raw materials

Tag:[2-(3,4-dimethylphenyl)-3-pyrrol-1-yl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-pyrazin-2-ylmethanone(1286725-49-2) Related Product Information

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