[3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine manufacturers
- PCAF-IN-2
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- $987.00
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2026-08-29
- CAS:56173-05-8
- Purity: 99.32%
- Supply Ability: 10g
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| | [3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine Basic information |
| | [3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine Chemical Properties |
| form | Solid | | color | White to off-white |
| | [3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine Usage And Synthesis |
| Uses | PCAF-IN-2 (compound 17) is a potent PCAF inhibitor with an IC50 value of 5.31 μM. PCAF-IN-2 shows anti-tumour activity. CAF-IN-2 induces apoptosis and arrest the cell cycle at the G2/M phase[1]. | | IC 50 | PCAF: 5.31 μM (IC50) | | References | [1] Turky A, et al. Design, synthesis, and antitumor activity of novel compounds based on 1,2,4-triazolophthalazine scaffold: Apoptosis-inductive and PCAF-inhibitory effects. Bioorg Chem. 2020 Aug;101:104019. DOI:10.1016/j.bioorg.2020.104019 |
| | [3-(trifluoromethyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]hydrazine Preparation Products And Raw materials |
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