4-HYDROPEROXY CYCLOPHOSPHAMIDE

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Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:4-hydroperoxy cyclophosphamide
CAS:39800-16-3
Purity:98% Package:1mg;230USD
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Products Intro: Product Name:4-Hydroperoxycyclophosphamide
CAS:39800-16-3
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Products Intro: Product Name:4-HYDROPEROXY CYCLOPHOSPHAMIDE
CAS:39800-16-3
Purity:98% Package:10mg; 25mg; 1mg; 5mg Remarks:Medbio
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Products Intro: Product Name:4-hydroperoxy Cyclophosphamide
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Products Intro: Product Name:4-Hydroperoxy CyclophosphaMide
CAS:39800-16-3
Package:50Mg,5Mg

4-HYDROPEROXY CYCLOPHOSPHAMIDE manufacturers
4-HYDROPEROXY CYCLOPHOSPHAMIDE Basic information
Product Name:4-HYDROPEROXY CYCLOPHOSPHAMIDE
Synonyms:4-HYDROPEROXY CYCLOPHOSPHAMIDE;,2-oxide;2-(bis(2-chloroethyl)amino)-4-hydroperoxytetrahydro-2h-1,3,2-oxazaphosphorin;2-oxazophosphorine,2-(bis(2-chloroethyl)amino)-4-hydroperoxytetrahydro-2h-3;4-hydroperoxyphosphamide;4-oohcyclophosphamide;perfosfaMide, 4-hydroperoxycyclophosphaMide;4-peroxy-cpa
CAS:39800-16-3
MF:C7H15Cl2N2O4P
MW:293.08
EINECS:
Product Categories:Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Phosphorylating and Phosphitylating Agents
Mol File:39800-16-3.mol
4-HYDROPEROXY CYCLOPHOSPHAMIDE Structure
4-HYDROPEROXY CYCLOPHOSPHAMIDE Chemical Properties
Melting point 100-103°C
Boiling point 419.9±55.0 °C(Predicted)
density 1.46±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -86°C Freezer, Under Inert Atmosphere
solubility Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly), DCM
form Solid
pka11.06±0.20(Predicted)
color White to Pale Yellow
Stability:Hygroscopic, Temperature Sensitive
InChIInChI=1S/C7H16Cl2N2O4P/c8-2-4-11(5-3-9)16(13)10-7(15-12)1-6-14-16/h7,10,12,16H,1-6H2/q-1/p-1
InChIKeyZZENMHFAKYKQCX-UHFFFAOYSA-M
SMILES[O-]OC1CCOP(N(CCCl)CCCl)([O-])N1
CAS DataBase Reference39800-16-3
Safety Information
WGK Germany WGK 3
Storage Class6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard ClassificationsAcute Tox. 3 Dermal
Acute Tox. 3 Oral
Carc. 1B
Eye Dam. 1
Muta. 1B
Repr. 1A
Skin Corr. 1B
Skin Sens. 1A
MSDS Information
4-HYDROPEROXY CYCLOPHOSPHAMIDE Usage And Synthesis
Chemical PropertiesWhite Solid
UsesA metabolite of Cyclophosphamide. Antineoplastic; bone marrow purging agent.
DefinitionChEBI: The active metabolite of the nitrogen mustard cyclophosphamide with potent antineoplastic and immunosuppressive properties.
Biological ActivityActive metabolite of the nitrogen mustard cyclophosphamide.
4-Hydroperoxycyclophosphamide is the active metabolite of the nitrogen mustard cyclophosphamide. 4-Hydroperoxycyclophosphamide exhibits potent antineoplastic and immunosuppressive activities.
in vivo

4-Hydroperoxy cyclophosphamide (200 mg/kg intraperitoneally injected) kills Caspase-independent T cells and B cells in mice[1].

Animal Model:BALB/c mice[1]
Dosage:200 mg/kg
Administration:i.p.
Result:Exhibited a marked depletion of immature double-positive CD4 t CD8 t thymocytes and mature single-positive CD4+ and CD8+ T cells.
4-HYDROPEROXY CYCLOPHOSPHAMIDE Preparation Products And Raw materials
Tag:4-HYDROPEROXY CYCLOPHOSPHAMIDE(39800-16-3) Related Product Information
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