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15(S)-15-Methyl prostaglandin

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15(S)-15-Methyl prostaglandin Basic information
Product Name:15(S)-15-Methyl prostaglandin
Synonyms:9ALPHA,11ALPHA,15S-TRIHYDROXY-15-METHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID, METHYL ESTER;15(S)-15-methylProstaglandinF2amethylester;15(S)-15-methylProstaglandinF2αmethylester;15(S)-15-METHYL PROSTAGLANDIN;Carboprost methyl ester;Methyl (E)-7-[(1S,3S,5R)-3,5-dihydroxy-2-[(Z,3S)-3-hydroxy-3-methyloct-1-enyl]cyclopentyl]hept-5-enoate;U-36384;15(s)15-methyl-pgf2-alphamethylester
CAS:35700-21-1
MF:C22H38O5
MW:382.53
EINECS:
Product Categories:
Mol File:35700-21-1.mol
15(S)-15-Methyl prostaglandin Structure
15(S)-15-Methyl prostaglandin Chemical Properties
Melting point 55-56°
alpha D +24° (c = 0.81 in ethanol)
Boiling point 429.67°C (rough estimate)
density 1.0323 (rough estimate)
refractive index 1.6120 (estimate)
storage temp. Store at -20°C
solubility DMF: >50 mg/ml (from PGE2 methyl es; DMSO: >50 mg/ml (from PGE2 methyl es; Ethanol: >50 mg/ml (from PGE2 methyl es; PBS pH 7.2: >5 mg/ml (from PGE2 methyl est
form A crystalline solid
pka14.657±0.29(predicted)
Safety Information
MSDS Information
15(S)-15-Methyl prostaglandin Usage And Synthesis
Uses15(S)-15-methyl PGF2α methyl ester is a derivative of 15(S)-15-methyl PGF2α with increased membrane permeability. Hydrolysis of the methyl ester in vivo releases the biologically active 15(S)-15-methyl PGF2α, which is a potent uterine stimulant and abortifacient.
UsesCarboprost Methyl Ester, used in combination with Misoprostol (M368755), can boost human preadipocyte proliferation, glycerolphosphate dehrydogenase (GPDH) up-regulation and lipid accumulation during differentiation. Also, mice treated with Carboprost Methyl Ester showed termination of early pregnancy and peristatic effects. This compound is suitable for pyruvate dehydrogenase (PDH) related research.
DefinitionChEBI: 15-methyl-15R-PGF2alpha methyl ester is a prostanoid.
15(S)-15-Methyl prostaglandin Preparation Products And Raw materials
Tag:15(S)-15-Methyl prostaglandin(35700-21-1) Related Product Information
Prostaglandin E1 Methyl acetate CHLOROPHOSPHONAZO III Prostaglandin E2 Methanol Methyl acrylate Basic Violet 1 Paraquat dichloride Methylparaben Kresoxim-methyl Acetonitrile Methyl Methyl bromide Dinoprost tromethamine Candicidin 15(R)-15-METHYL PROSTAGLANDIN E2 Carboprost 1-METHOXY-9ALPHA, 11ALPHA, 15S-TRIHYDROXYPROSTA-5Z, 13E-DIENE