| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:TP0438836
CAS:957772-01-9
Package:1removed
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TP0438836 manufacturers
- TP0438836
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- $1820.00
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2026-04-21
- CAS:957772-01-9
- Purity:
- Supply Ability: 10g
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| | TP0438836 Basic information |
| Product Name: | TP0438836 | | Synonyms: | TP0438836;Urea, N-[2-[4-[(5-β-D-glucopyranosyl-4-hydroxy-2-methylphenyl)methyl]phenyl]ethyl]-N'-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]- | | CAS: | 957772-01-9 | | MF: | C27H38N2O10 | | MW: | 550.61 | | EINECS: | | | Product Categories: | | | Mol File: | 957772-01-9.mol |  |
| | TP0438836 Chemical Properties |
| Boiling point | 937.9±65.0 °C(Predicted) | | density | 1.419±0.06 g/cm3(Predicted) | | pka | 10.20±0.10(Predicted) |
| | TP0438836 Usage And Synthesis |
| Description | TP0438836 is a potent, low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor for the treatment of type 2 diabetes. TP0438836 showed IC50 values 28nM and 7 nM for hSGLT1 and hSGLT2 resepctively. | | Uses | TP0438836 (compound 30b) is a SGLT1 inhibitor, with IC50 values of 28 nM and 7 nM for hSGLT1 and hSGLT2, respectively. TP0438836 can be used in diabetes research[1]. | | IC 50 | hSGLT1: 28 nM (IC50); hSGLT2: 7 nM (IC50) | | References | [1] Kuroda S, et al. Discovery of a potent, low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor (TP0438836) for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2018 Dec 1;28(22):3534-3539. DOI:10.1016/j.bmcl.2018.09.035 |
| | TP0438836 Preparation Products And Raw materials |
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