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Ontores Biotech |
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| | Cyclosporin A-Derivative 2 Basic information |
| Product Name: | Cyclosporin A-Derivative 2 | | Synonyms: | Cyclosporin A-Derivative 2;Glycine, L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-, methyl ester;L-Valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycineMe;Des(N-Methyl-leucyl) Cyclosporin A seco(MeGly-MeLeu) Methyl Ester | | CAS: | 156047-45-9 | | MF: | C58H104N10O13 | | MW: | 1149.51 | | EINECS: | | | Product Categories: | | | Mol File: | 156047-45-9.mol |  |
| | Cyclosporin A-Derivative 2 Chemical Properties |
| Boiling point | 1147.8±65.0 °C(Predicted) | | density | 1.105±0.06 g/cm3(Predicted) | | solubility | Acetone, DCM, Methanol | | form | Solid | | pka | 13.07±0.46(Predicted) | | color | Yellow |
| | Cyclosporin A-Derivative 2 Usage And Synthesis |
| Uses | L-Valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester is an intermediate in the synthesis of Cyclosporin AM 4N (C989410), a metabolite of Cyclosporin A (C988900). Cyclosporin A is a hydrophobic cyclic undecapeptide that is used as a potent immunosuppressive agent that has application in human organ transplantation. Cyclosporin A works by inhibiting subsets of T lymphocytes to facilitate organ transplantation. |
| | Cyclosporin A-Derivative 2 Preparation Products And Raw materials |
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