DMPAC-Chol manufacturers
- DMPAC-Chol
-
- $395.00
-
2026-05-11
- CAS:184582-91-0
- Purity:
- Supply Ability: 10g
|
| | DMPAC-Chol Basic information |
| Product Name: | DMPAC-Chol | | Synonyms: | DMPAC-Chol;DMPAC Chol,DMPACChol;Cholest-5-en-3-ol (3β)-, 3-[[3-(dimethylamino)propyl]carbamate];(3β)-cholest-5-en-3-ol 3-[[3-(dimethylamino)propyl]carbamate | | CAS: | 184582-91-0 | | MF: | C33H58N2O2 | | MW: | 514.84 | | EINECS: | | | Product Categories: | | | Mol File: | 184582-91-0.mol |  |
| | DMPAC-Chol Chemical Properties |
| Boiling point | 591.2±39.0 °C(Predicted) | | density | 1.01±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF:10.0(Max Conc. mg/mL);19.42(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);19.42(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:6):0.14(Max Conc. mg/mL);0.27(Max Conc. mM) | | form | A crystalline solid | | pka | 12.49±0.46(Predicted) |
| | DMPAC-Chol Usage And Synthesis |
| Description | DMPAC-Chol is a cationic cholesterol derivative that has been used in liposome formation for gene transfection. Liposomes containing DMPAC-chol bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA when used at lipsome:DNA ratios ranging from 2.5:1 to 10:1 w/w. DMPAC-Chol-containing liposomes also reduce viability of HepG2 cells by 63% when used at a concentration of 37.5 μg/ml. | | Uses | DMPAC-Chol (Chol-T) is used for liposome formation. DMPAC-Chol (Chol-T) liposomes exhibits great transfection effciencies[1]. | | References | [1] Neermala Kisoon, et al. A novel cationic cholesterol derivative, its formulation into liposomes, and the efficient transfection of the transformed human cell lines HepG2 and HeLa. Drug Deliv. 2002 Jul-Sep;9(3):161-7. DOI:10.1080/15227950290097598 |
| | DMPAC-Chol Preparation Products And Raw materials |
|