CATHEPSIN INHIBITOR III manufacturers
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| | CATHEPSIN INHIBITOR III Basic information |
| Product Name: | CATHEPSIN INHIBITOR III | | Synonyms: | CATHEPSIN INHIBITOR III;Z-FG-NHO-BZPOME;Z-PHE-GLY-NHO-BZ-POME;Glycinamide, N-[(phenylmethoxy)carbonyl]-L-phenylalanyl-N-[(4-methoxybenzoyl)oxy]-;Z-FG-NHO-BzOME | | CAS: | 180313-86-4 | | MF: | C27H27N3O7 | | MW: | 505.52 | | EINECS: | | | Product Categories: | | | Mol File: | 180313-86-4.mol |  |
| | CATHEPSIN INHIBITOR III Chemical Properties |
| density | 1.275±0.06 g/cm3(Predicted) | | storage temp. | 10-30°C | | solubility | ethanol: 1mg/mL DMSO: 5mg/mL | | pka | 11.07±0.46(Predicted) | | form | Solid | | color | White to off-white |
| WGK Germany | WGK 1 | | Storage Class | 11 - Combustible Solids |
| | CATHEPSIN INHIBITOR III Usage And Synthesis |
| Uses | Z-FG-NHO-BzOME is a cysteine protease inhibitor that selectively inhibits cathepsin B, cathepsin L, cathepsin S, and papain[1]. | | Biological Activity | Cell permeable: no', 'Primary Target cathepsin B', 'Product does not compete with ATP.', 'Reversible: no', 'k2/Ki = 1 x 10⁴ M-¹ sec-¹ | | References | [1] Rajgopal Yadavalli, et al. Calpain-dependent endoproteolytic cleavage of PrPSc modulates scrapie prion propagation. J Biol Chem. 2004 May 21;279(21):21948-56. DOI:10.1074/jbc.M400793200 |
| | CATHEPSIN INHIBITOR III Preparation Products And Raw materials |
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