- Secalciferol
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- $7.00
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2020-02-18
- CAS:55721-11-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100kg
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| | Secalciferol Basic information |
| Product Name: | Secalciferol | | Synonyms: | Stilbitol;(24r)-hydroxycalcidiol;(3-beta,5z,7e,24r)-9,10-secocholesta-5,7,10(19)-triene-3,24,25-triol;ANTI-VEGFR2 (FLK1/KDR)(C-TERMINAL) antibody produced in rabbit;Secalciferol/ 24R, 25-Dihydroxycholecalciferol;Secalciferol, 24R,25-dihydroxycholecalciferol, 24R,25-dihydroxyvitamin D3, 24R
25 DHCC;24(r),25-dihydroxycholecalciferol;7,10(19)-triene-3,24,25-triol,(3-beta,5z,7e,24r)-10-secocholesta-5 | | CAS: | 55721-11-4 | | MF: | C27H44O3 | | MW: | 416.64 | | EINECS: | | | Product Categories: | Chiral Reagents;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals;Other APIs;APIs | | Mol File: | 55721-11-4.mol |  |
| | Secalciferol Chemical Properties |
| Melting point | 63-65°C | | Boiling point | 474.91°C (rough estimate) | | density | 1.0362 (rough estimate) | | refractive index | 1.4700 (estimate) | | storage temp. | Amber Vial, -20°C Freezer, Under Inert Atmosphere | | solubility | Soluble in DMSO | | form | Powder | | pka | 14.67±0.29(Predicted) | | color | White to off-white | | biological source | synthetic | | BRN | 4567039 | | Stability: | Light Sensitive, Temperature Sensitive | | InChIKey | FCKJYANJHNLEEP-AOWQBJNISA-N | | SMILES | CC(C)(O)[C@H](O)CC[C@H]([C@@H]1[C@]2(C)[C@]([H])(/C(=C/C=C3/C[C@@H](O)CCC/3=C)/CCC2)CC1)C |
| Hazard Codes | T+ | | Risk Statements | 28 | | Safety Statements | 28-36/37-45 | | RIDADR | 2811 | | WGK Germany | 3 | | RTECS | VS2895000 | | Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | | Hazard Classifications | Acute Tox. 2 Inhalation
Acute Tox. 3 Dermal
Acute Tox. 3 Oral
STOT RE 1 Oral |
| | Secalciferol Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | A labelled metabolite of Vitamin D, a possible anti-inflammatory steroid. | | Uses | A labelled metabolite of Vitamin D, a possibly anti-inflammatory steroid. | | Uses | A metabolite of Vitamin D, a possibly anti-inflammatory steroid. | | Definition | ChEBI: (24R)-24,25-dihydroxycalciol is a seco-cholestane, a hydroxy seco-steroid and a hydroxycalciol. It has a role as a human metabolite. | | Brand name | Osteo D (Teva, Israel). | | Biological Activity | (24R)-24,25-Dihydroxyvitamin D3 plays an essential role in calcium and phosphorus homeostasis. (24R)-24,25-Dihydroxyvitamin D3 along with 1α,25(OH)2D3 stimulates bone metabolism.', 'Cholecalciferol is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs. 1α-Hydroxyvitamin D3 (alfacalcidol) is a synthetic analog th at is metabolized to 1,25-dihydroxycholecalciferol, the biologically active form of vitamin D3. Other analogues of cholecalciferol result from different hydroxylations. 24R,25-Dihydroxyvitamin D3 is a catabolite of 25-Dihydroxyvitamin D3 and a putative regulator of developmental bone formation. 24R,25-Dihydroxyvitamin D3 is a substrate for renal 25-hydroxyvitamin D3 1 α-hydroxylase. 24R,25-Dihydroxyvitamin D3 is an endogenous regulator of apo A-I synthesis through a VDR-independent signaling mechanism and an inhibitor of Pi-induced apoptosis through Ca2+, PLD, and PLC signaling and through LPA-LPA1/3-G(αi)-PI(3)K-mdm2-mediated p53 degradation. |
| | Secalciferol Preparation Products And Raw materials |
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