DSP-2230 manufacturers
- DSP-2230
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- $64.00
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2026-08-15
- CAS:1233231-30-5
- Purity: 99.68%
- Supply Ability: 10g
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| | DSP-2230 Basic information |
| Product Name: | DSP-2230 | | Synonyms: | DSP-2230;DSP2230; DSP 2230; DSP-2230;Inhibitor,inhibit,Na+ channels,Sodium Channel,DSP 2230,Na channels,DSP2230,DSP-2230;Propanamide, 2-[[[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)-3H-imidazo[4,5-b]pyridin-2-yl]methyl]amino]-, (2S)-;(2S)-2-({[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}amino)propanamide;DSP-2230, 10 mM in DMSO | | CAS: | 1233231-30-5 | | MF: | C20H20F3N5O2 | | MW: | 419.4 | | EINECS: | | | Product Categories: | | | Mol File: | 1233231-30-5.mol |  |
| | DSP-2230 Chemical Properties |
| Boiling point | 607.8±55.0 °C(Predicted) | | density | 1.53±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO:125.0(Max Conc. mg/mL);298.04(Max Conc. mM) | | form | Solid | | pka | 15.94±0.50(Predicted) | | color | White to off-white | | InChIKey | HHXCJIMPEJSJTG-JTQLQIEISA-N | | SMILES | C(N)(=O)[C@@H](NCC1=NC2=CC=C(OC3=CC(F)=C(F)C(F)=C3)N=C2N1C1CCC1)C |
| | DSP-2230 Usage And Synthesis |
| Uses | DSP-2230 is a selective Nav1.7/Nav1.8 blocker, can be used to improve neuropathic pain[1][2][3]. | | IC 50 | Nav1.7; Nav1.8 | | References | [1] Bagal SK, et al. Voltage gated sodium channels as drug discovery targets. Channels (Austin). 2015;9(6):360-6. DOI:10.1080/19336950.2015.1079674
[2] Sara Sabina Hadida-Ruah, et al. Sulfonamides as modulators of sodium channels.
[3] Matthew Alsaloum, et al. Status of peripheral sodium channel blockers for non-addictive pain treatment. Nat Rev Neurol. 2020 Dec;16(12):689-705. DOI:10.1038/s41582-020-00415-2 |
| | DSP-2230 Preparation Products And Raw materials |
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