2-Quinoxaline-5,6,7,8-d4-carboxylic acid, 3-methyl- manufacturers
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| | 2-Quinoxaline-5,6,7,8-d4-carboxylic acid, 3-methyl- Basic information |
| Product Name: | 2-Quinoxaline-5,6,7,8-d4-carboxylic acid, 3-methyl- | | Synonyms: | 2-Quinoxaline-5,6,7,8-d4-carboxylic acid, 3-methyl-;3-Methyl-2-quinoxalinecarboxylic Acid-d4;3-Methyl-quinoxaline-2-carboxylic Acid-d4 （MQCA-d4）;3-Methyl-2-quinoxalinecarboxylic acid-d;3-Methyl(2H)quinoxaline-2-carboxylic acid;MQCA-d4 | | CAS: | 2244217-93-2 | | MF: | C10H4D4N2O2 | | MW: | 192.207367112 | | EINECS: | | | Product Categories: | | | Mol File: | 2244217-93-2.mol |  |
| | 2-Quinoxaline-5,6,7,8-d4-carboxylic acid, 3-methyl- Chemical Properties |
| form | Solid | | color | Off-white to light brown |
| | 2-Quinoxaline-5,6,7,8-d4-carboxylic acid, 3-methyl- Usage And Synthesis |
| Uses | 3-Methyl-2-quinoxalinecarboxylic acid-d4 is the deuterium labeled 3-Methyl-2-quinoxalinecarboxylic acid. 3-Methyl-2-quinoxalinecarboxylic acid (MQCA), an important N-oxide reductive metabolite of Quinocetone or Olaquindox, potently inhibits the growth of Chang liver cells through S phase arrest of the cell cycle[1]. | | References | [1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Keyu Zhang , et al. Cytotoxicity and Genotoxicity of 1,4-bisdesoxyquinocetone, 3-methylquinoxaline-2-carboxylic Acid (MQCA) in Human Hepatocytes. Res Vet Sci. 2012 Dec;93(3):1393-401. DOI:10.1016/j.rvsc.2012.06.012 |
| | 2-Quinoxaline-5,6,7,8-d4-carboxylic acid, 3-methyl- Preparation Products And Raw materials |
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