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| Product Name: | VAV1 antibody | | Synonyms: | VAV1 antibody;Mouse Monoclonal VAV1 Antibody | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![VAV1 antibody Structure]() |
| | VAV1 antibody Chemical Properties |
| | VAV1 antibody Usage And Synthesis |
| Source | Rabbit | | Reactivity | Mouse;Rat;Human | | Background | Vav proteins belong to the Dbl family of guanine nucleotide exchange factors for Rho/Rac small GTPases. The three identified mammalian Vav proteins differ in their expression. Vav1 is expressed only in hematopoietic cells and is involved in the formation of the immune synapse. Vav2 and Vav3 are more ubiquitously expressed. Vav proteins contain the Dbl homology domain, which confers GEF activity, as well as protein interaction domains that allow them to function in pathways regulating actin cytoskeleton organization. Phosphorylation stimulates the GEF activity of Vav protein towards Rho/Rac. | | References | [1] Hornstein, I. et al. (2004) Cell. Signal. 16, 1-11.
[2] Crespo, P. et al. (1997) Nature 385, 169-172.
[3] Han, J. et al. (1997) Mol. Cell. Biol. 17, 1346-1353. |
| | VAV1 antibody Preparation Products And Raw materials |
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