SSTR5 ANTAGONIST 2 TFA
| 中文名称 | SSTR5 ANTAGONIST 2 TFA |
|---|---|
| 中文同义词 | 化合物 SSTR5 antagonist 2 TFA |
| 英文名称 | SSTR5 antagonist 2 TFA |
| 英文同义词 | SSTR5 antagonist 2 TFA |
| CAS号 | 1254733-98-6 |
| 分子式 | C34H36F4N2O7 |
| 分子量 | 660.66 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1254733-98-6.mol |
| 结构式 |  |
SSTR5 ANTAGONIST 2 TFA 性质
SSTR5 antagonist 2 TFA (compound 10) 是强效的、具有口服活性的生长激素抑制激素(受体)亚型 5 (SSTR5) 的选择性拮抗剂，有潜力用于 2 型糖尿病的研究。
SSTR5.
SSTR5 antagonist 2 (10 mg/kg, orally) increases both total and active circulating incretin hormone GLP1 levels in mice at a dose of 10 mg/kg.
SSTR5 antagonist 2 increases pancreatic insulin secretion as well as total and active GLP1 release, and demonstrates synergistic effects in combination with DPP4 inhibitors.
| Animal Model: | Rodent diabetic model without risk of hypoglycemia. |
| Dosage: | 10 mg/kg. |
| Administration: | Orally. |
| Result: | Increased both total and active circulating incretin hormone GLP1 levels. |