Methyltetrazine-PEG24-amine

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Methyltetrazine-PEG24-amine Suppliers list
Company Name: TargetMol Chemicals Inc.  
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Methyltetrazine-PEG24-amine Basic information
Product Name:Methyltetrazine-PEG24-amine
Synonyms:Methyltetrazine-PEG24-amine;Poly(oxy-1,2-ethanediyl), α-(2-aminoethyl)-ω-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-
CAS:2353410-18-9
MF:(C2H4O)nC11H13N5O
MW:0
EINECS:
Product Categories:
Mol File:2353410-18-9.mol
Methyltetrazine-PEG24-amine Structure
Methyltetrazine-PEG24-amine Chemical Properties
solubility Soluble in Water, DMSO, DCM, DMF
Safety Information
MSDS Information
Methyltetrazine-PEG24-amine Usage And Synthesis
DescriptionMethyltetrazine-PEG24-amine is a monodisperse, click chemistry PEG linker containing a free amine and a methyltetrazine group. It is highly soluble in water. Amine (NH2) is reactive with carboxylic acid containing molecule in the presence of reagnet such as EDC or HATU. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene)
UsesMethyltetrazine-PEG24-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Methyltetrazine-PEG24-amine Preparation Products And Raw materials
Tag:Methyltetrazine-PEG24-amine(2353410-18-9) Related Product Information
TCO-PEG4-NHS Ester Tranexamic Acid 15-hexadecynoic acid (S)-2-Aminohex-5-ynoic acid Azido-PEG4-CH2CO2-NHS 1-(3-mercapto-1-oxopropoxy)-2,5-pyrrolidinedione