Benzamide, N-methyl-3-[[[4-(4-pyridinyl)benzoyl]amino]methyl]-

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Benzamide, N-methyl-3-[[[4-(4-pyridinyl)benzoyl]amino]methyl]- Suppliers list
Company Name: TargetMol Chemicals Inc.  
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Company Name: Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd  
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Company Name: Jinan Jiuli Biotechnology Co. , Ltd.  
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Company Name: TargetMol Chemicals Inc.  
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Email: sales@ubiochem.com

Benzamide, N-methyl-3-[[[4-(4-pyridinyl)benzoyl]amino]methyl]- manufacturers

  • PF-4950834
  • PF-4950834 pictures
  • $2500.00
  • 2026-07-15
  • CAS:1256264-62-6
  • Purity:
  • Supply Ability: 10g
Benzamide, N-methyl-3-[[[4-(4-pyridinyl)benzoyl]amino]methyl]- Basic information
Product Name:Benzamide, N-methyl-3-[[[4-(4-pyridinyl)benzoyl]amino]methyl]-
Synonyms:Benzamide, N-methyl-3-[[[4-(4-pyridinyl)benzoyl]amino]methyl]-;PF 4950834;PF4950834;PF-4950834
CAS:1256264-62-6
MF:C21H19N3O2
MW:345.39
EINECS:
Product Categories:
Mol File:1256264-62-6.mol
Benzamide, N-methyl-3-[[[4-(4-pyridinyl)benzoyl]amino]methyl]- Structure
Benzamide, N-methyl-3-[[[4-(4-pyridinyl)benzoyl]amino]methyl]- Chemical Properties
Boiling point 619.7±55.0 °C(Predicted)
density 1.193±0.06 g/cm3(Predicted)
pka13.28±0.46(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
Benzamide, N-methyl-3-[[[4-(4-pyridinyl)benzoyl]amino]methyl]- Usage And Synthesis
UsesPF-4950834 is a potent, selective, orally bioavailable, ATP-competitive rho kinase inhibitor with IC50 values of 8.35 nM and 33.12 nM against ROCK2 and ROCK1, respectively. PF-4950834 inhibits neutrophil migration[1].
IC 50ROCK2: 8.35 nM (IC50); ROCK1: 33.12 nM (IC50); PKA: 424 nM (IC50); PKCη: 756 nM (IC50)
References[1] Rajagopalan LE, et al. Biochemical, cellular, and anti-inflammatory properties of a potent, selective, orally bioavailable benzamide inhibitor of Rho kinase activity. J Pharmacol Exp Ther. 2010 Jun;333(3):707-16. DOI:10.1124/jpet.110.166033
Benzamide, N-methyl-3-[[[4-(4-pyridinyl)benzoyl]amino]methyl]- Preparation Products And Raw materials
Tag:Benzamide, N-methyl-3-[[[4-(4-pyridinyl)benzoyl]amino]methyl]-(1256264-62-6) Related Product Information
4-Pyridinecarboxamide, N-[(3-hydroxyphenyl)methyl]- 4-Formyl-N-(3-pyridinylmethyl)benzamide N-(2-Amino-ethyl)-isonicotinamide piperazin-1-yl(pyridin-4-yl)methanone dihydrochloride Benzamide, N-methyl-3-[[[4-(4-pyridinyl)benzoyl]amino]methyl]- Benzamide, 4-(4-pyridinyl)-