2,4(1H,3H)-Pyrimidinedione, 1-(cyclopropylmethyl)-6-(3,5-dimethylbenzoyl)-5-(1-methylethyl)-

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2,4(1H,3H)-Pyrimidinedione, 1-(cyclopropylmethyl)-6-(3,5-dimethylbenzoyl)-5-(1-methylethyl)- manufacturers

  • IQP-0528
  • IQP-0528 pictures
  • $48.00
  • 2026-07-27
  • CAS:301297-45-0
  • Purity: 98.36%
  • Supply Ability: 10g
2,4(1H,3H)-Pyrimidinedione, 1-(cyclopropylmethyl)-6-(3,5-dimethylbenzoyl)-5-(1-methylethyl)- Basic information
Product Name:2,4(1H,3H)-Pyrimidinedione, 1-(cyclopropylmethyl)-6-(3,5-dimethylbenzoyl)-5-(1-methylethyl)-
Synonyms:2,4(1H,3H)-Pyrimidinedione, 1-(cyclopropylmethyl)-6-(3,5-dimethylbenzoyl)-5-(1-methylethyl)-;IQP 0528;IQP0528;SJ3991;SJ-3991;Ainuovirine Impurity 2;IQP-0528, 10 mM in DMSO;IQP-0528
CAS:301297-45-0
MF:C20H24N2O3
MW:340.42
EINECS:
Product Categories:
Mol File:301297-45-0.mol
2,4(1H,3H)-Pyrimidinedione, 1-(cyclopropylmethyl)-6-(3,5-dimethylbenzoyl)-5-(1-methylethyl)- Structure
2,4(1H,3H)-Pyrimidinedione, 1-(cyclopropylmethyl)-6-(3,5-dimethylbenzoyl)-5-(1-methylethyl)- Chemical Properties
Melting point 215-217 °C
density 1+-.0.06 g/cm3(Predicted)
pka8.91±0.40(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
2,4(1H,3H)-Pyrimidinedione, 1-(cyclopropylmethyl)-6-(3,5-dimethylbenzoyl)-5-(1-methylethyl)- Usage And Synthesis
UsesIQP-0528 is a highly potent nonnucleoside reverse transcriptase inhibitor (NNRTI). IQP-0528 shows nanomolar activity against both HIV-1 and HIV-2, with an HIV-1 EC50 of 0.2 nM and an HIV-2 EC50 of 100 nM[1].
IC 50HIV-1; HIV-2
References[1] Su JT, et al. A Dose Ranging Pharmacokinetic Evaluation of IQP-0528 Released from Intravaginal Rings in Non-Human Primates. Pharm Res. 2017;34(10):2163-2171. DOI:10.1007/s11095-017-2224-1
2,4(1H,3H)-Pyrimidinedione, 1-(cyclopropylmethyl)-6-(3,5-dimethylbenzoyl)-5-(1-methylethyl)- Preparation Products And Raw materials
Tag:2,4(1H,3H)-Pyrimidinedione, 1-(cyclopropylmethyl)-6-(3,5-dimethylbenzoyl)-5-(1-methylethyl)-(301297-45-0) Related Product Information
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