Saralasin (trifluoroacetate salt)

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Saralasin (trifluoroacetate salt) Basic information
Product Name:Saralasin (trifluoroacetate salt)
Synonyms:Saralasin (trifluoroacetate salt)
CAS:
MF:
MW:0
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Mol File:Mol File
Saralasin (trifluoroacetate salt) Structure
Saralasin (trifluoroacetate salt) Chemical Properties
solubility DMSO: 5 mg/mlPBS (pH 7.2): 10 mg/ml
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MSDS Information
Saralasin (trifluoroacetate salt) Usage And Synthesis
DescriptionSaralasin is a peptide angiotensin II type 2 (AT2) receptor agonist.1 It binds to AT2 receptors (Ki = 0.38 nM) and induces neurite outgrowth in NG108-15 cells when used at a concentration at 100 nM, an effect that can be inhibited by the AT2 receptor antagonist PD 123310. Saralasin (5 µg/animal, i.c.v.) enhances acquisition of the conditioned avoidance response in rats.2WARNING This product is not for human or veterinary use.
References[1] MARIE-ODILE GUIMOND. Saralasin and Sarile Are AT2 Receptor Agonists[J]. ACS Medicinal Chemistry Letters, 2014, 5 10: 1129-1132. DOI: 10.1021/ml500278g
[2] JOHN W. WRIGHT  Jospeh W H. Brain angiotensin receptor subtypes AT1, AT2, and AT4 and their functions[J]. Regulatory Peptides, 1995, 59 3: Pages 269-295. DOI: 10.1016/0167-0115(95)00084-o
Saralasin (trifluoroacetate salt) Preparation Products And Raw materials
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