Propanoic acid, 2-[3-[[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl]phenoxy]-, (2S)- manufacturers
- MLR24
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- $2180.00
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2026-07-27
- CAS:393794-17-7
- Purity:
- Supply Ability: 10g
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| | Propanoic acid, 2-[3-[[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl]phenoxy]-, (2S)- Basic information |
| | Propanoic acid, 2-[3-[[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl]phenoxy]-, (2S)- Chemical Properties |
| Boiling point | 585.5±50.0 °C(Predicted) | | density | 1.31±0.1 g/cm3(Predicted) | | storage temp. | RT | | solubility | Soluble in DMSO (up to 30 mg/ml) | | pka | 3.22±0.10(Predicted) | | form | solid | | color | White | | Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
| | Propanoic acid, 2-[3-[[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl]phenoxy]-, (2S)- Usage And Synthesis |
| Description | MRL-24 (393794-17-7) displays high affinity for PPARγ with excellent anti-diabetic activity in mice but poor PPARγ agonist activity in transcription and adipogenesis assays. MRL-24 is highly effective (30 nM) at blocking Cdk5-mediated phosphorylation of PPARγ. Cell permeable. | | Uses | MRL-24 is a PPARγ agonist. MRL-24 can be used in metabolic disease related research[1]. | | IC 50 | PPARγ | | References | [1] WEBB P. Faculty Opinions recommendation of Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5.[C]. 2010: 0. DOI:10.3410/f.4305956.4618058 |
| | Propanoic acid, 2-[3-[[1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl]methyl]phenoxy]-, (2S)- Preparation Products And Raw materials |
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