Ornipressin Acetate manufacturers
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| | Ornipressin Acetate Basic information |
| Product Name: | Ornipressin Acetate | | Synonyms: | Orpressin;Ornipressin Acetate（3397 23 7，free）,Ornipressin Acetate（3397237，free）;Ornipressin acetate salt | | CAS: | 914453-98-8 | | MF: | C47H67N13O14S2 | | MW: | 1102.25 | | EINECS: | | | Product Categories: | | | Mol File: | 914453-98-8.mol |  |
| | Ornipressin Acetate Chemical Properties |
| storage temp. | -20°C | | solubility | DMSO: 10 mg/mlPBS (pH 7.2): 20 mg/ml | | form | powder | | color | white to off-white | | Sequence | Cys-Tyr-Phe-Gln-Asn-Cys-Pro-{Orn}-Gly-NH2 (Disulfide bridge: Cys1-Cys6) | | InChIKey | AYJSELDHDXYDKX-HPILINOVSA-N |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | Ornipressin Acetate Usage And Synthesis |
| Uses | An acetate salt of ornipressin, a pharmaceutical peptide used as a vasoconstrictor in the treatment of type 1 hepatorenal syndrome. | | Biological Activity | Ornipressin is a potent vasoconstrictor agent used in surgery for hemostasis and in regional anesthesia for prolongation of nerve block. Ornipressin is a vasopressin agonist specific for the V1 receptor with low antidiuretic activity. | | References | [1] P. KAM T. T. The pharmacology of ornipressin (POR–8): a local vasoconstrictor used in surgery[J]. European Journal of Anaesthesiology, 2004, 15 2: 133-139. DOI: 10.1111/j.0265-0215.1998.00247.x
[2] KAZIMIERZ WIŚNIEWSKI*. New, Potent, Selective, and Short-Acting Peptidic V1a Receptor Agonists[J]. Journal of Medicinal Chemistry, 2011, 54 13: 4388-4398. DOI: 10.1021/jm200278m |
| | Ornipressin Acetate Preparation Products And Raw materials |
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