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| | N,N'-dimethyl-N-[2-(methylamino)ethyl]ethylenediamine Basic information |
| Product Name: | N,N'-dimethyl-N-[2-(methylamino)ethyl]ethylenediamine | | Synonyms: | N,N'-dimethyl-N-[2-(methylamino)ethyl]ethylenediamine;1,4,7-TRIMETHYLDIETHYLENETRIAMINE;2,2'-(Methylimino)bis(N-methylethanamine);Methylbis[2-(methylamino)ethyl]amine;N,N'-Dimethyl-N-[2-(methylamino)ethyl]-1,2-ethanediamine;N,N'-dimethyl-N-[2-(;Methyl(2-{Methyl[2-(MethylaMino)ethyl]aMino}ethyl)aMine;N,N',N''-Trimethyldiethylenetriamine | | CAS: | 105-84-0 | | MF: | C7H19N3 | | MW: | 145.25 | | EINECS: | 203-337-3 | | Product Categories: | Polyamines | | Mol File: | 105-84-0.mol | ![N,N'-dimethyl-N-[2-(methylamino)ethyl]ethylenediamine Structure](CAS/GIF/105-84-0.gif) |
| | N,N'-dimethyl-N-[2-(methylamino)ethyl]ethylenediamine Chemical Properties |
| RIDADR | UN 2735 8/PG II | | TSCA | TSCA listed | | HS Code | 2921.29.0055 | | HazardClass | 8 | | PackingGroup | II |
| | N,N'-dimethyl-N-[2-(methylamino)ethyl]ethylenediamine Usage And Synthesis |
| Synthesis | The general procedure for the synthesis of N,N',N''-trimethyldiethylenetriamine from the compound (CAS: 1204417-39-9) is as follows:
Step 1: N,N-(2,2'-(methylureido)bis(ethane-2,1-diyl))bis(N-methyl-2-nitrobenzenesulfonamide) 7a (1.24 g, 2.405 mmol), cesium carbonate (2.35 g, 7.215 mmol, 3 eq.), and benzenethiol (795 mg, 7.215 mmol, 3 eq.) were dissolved in DMF (25 mL ) in DMF (25 mL) and the reaction was stirred at room temperature for 1 hour.
Step 2: Upon completion of the reaction, the reaction mixture was filtered and the filtrate was upsampled onto an MP-TsOH column pre-washed with dichloromethane (DCM).
Step 3: The cartridge was washed several times with DCM until the eluate was colorless, followed by elution of the target product with a methanol solution containing NH3.
Step 4: The eluate was collected and concentrated to afford N,N'-dimethyl-N-(2-(methylamino)ethyl)ethane-1,2-diamine 7b (220 mg, 63% yield), which was used directly in the next step of the reaction; Mass Spectrum (m/z) = 146 (M + H)+. | | References | [1] Patent: WO2010/3658, 2010, A1. Location in patent: Page/Page column 47-48 |
| | N,N'-dimethyl-N-[2-(methylamino)ethyl]ethylenediamine Preparation Products And Raw materials |
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