| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:IACS-8803 disodium
CAS:2243079-36-7
Purity:98% Remarks:Reach out to us for more information about custom solutions.
|
| Company Name: |
Shanghai Tachizaki Biomedical Research Center
|
| Tel: |
18014399201 |
| Email: |
sales@chemlab-tachizaki.com |
| Products Intro: |
Product Name:IACS-8803 disodium
CAS:2243079-36-7
Purity:98% HPLC Package:5mg，25mg，100mg，250mg，1g，10g+
|
| Company Name: |
Zhejiang Huida Biotech Co., Ltd.
|
| Tel: |
0571-89903022 18679456698 |
| Email: |
zilong@hizyme.com |
| Products Intro: |
Product Name:IACS-8803 disodium
CAS:2243079-36-7
Purity:>=98% Package:1mg
|
|
| | IACS-8803 disodium Basic information |
| | IACS-8803 disodium Chemical Properties |
| storage temp. | Store at -20°C, stored under nitrogen | | form | Solid | | color | White to off-white | | Water Solubility | Water : 56.67 mg/mL (76.74 mM; Need ultrasonic) |
| | IACS-8803 disodium Usage And Synthesis |
| Uses | IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 disodium has a robust systemic antitumor efficacy[1]. | | Biological Activity | IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 disodium has a robust systemic antitumor efficacy[1].
IACS-8803 (10 μg; intra-tumoral injection) shows superior antitumor activity in mice bearing bilateral B16-OVA melanomas[1]. | | in vivo | IACS-8803 (10 μg; intra-tumoral injection) shows superior antitumor activity in mice bearing bilateral B16-OVA melanomas[1]. | | References | [1]. Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640. |
| | IACS-8803 disodium Preparation Products And Raw materials |
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