| Company Name: |
BOC Sciences |
| Tel: |
16314854226; +8616314854226 |
| Email: |
inquiry@bocsci.com |
Fosciclopirox manufacturers
- Fosciclopirox
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- $48.00
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2026-08-03
- CAS:1380539-06-9
- Purity: 99.65%
- Supply Ability: 10g
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| | Fosciclopirox Basic information |
| Product Name: | Fosciclopirox | | Synonyms: | Fosciclopirox;CPX-POM;γ-secretase,Fosciclopirox,Gamma secretase,Inhibitor,inhibit;2(1H)-Pyridinone, 6-cyclohexyl-4-methyl-1-[(phosphonooxy)methoxy]-;((6-Cyclohexyl-4-methyl-2-oxopyridin-1(2H)-yl)oxy)methyl dihydrogen phosphate;Fosciclopirox, 10 mM in DMSO | | CAS: | 1380539-06-9 | | MF: | C13H20NO6P | | MW: | 317.27 | | EINECS: | | | Product Categories: | | | Mol File: | 1380539-06-9.mol |  |
| | Fosciclopirox Chemical Properties |
| Boiling point | 484.8±55.0 °C(Predicted) | | density | 1.38±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 100 mg/mL (315.19 mM; Need ultrasonic) | | pka | 1.68±0.10(Predicted) | | form | Solid | | color | Off-white to light yellow |
| | Fosciclopirox Usage And Synthesis |
| Uses | Fosciclopirox suppresses growth of urothelial cancer by targeting the γ-secretase complex. Fosciclopirox selectively delivers the active metabolite, Ciclopirox (CPX), to the entire urinary tract[1][2]. Ciclopirox has anticancer activity in a number of solid and hematologic malignancies. | | References | [1] Weir SJ, et al. Fosciclopirox suppresses growth of high-grade urothelial cancer by targeting the γ-secretase complex. Cell Death Dis. 2021 May 31;12(6):562. DOI:10.1038/s41419-021-03836-z
[2] Weir SJ, Wood R, Schorno K, Brinker AE, Ramamoorthy P, Heppert K, Rajewski L, Tanol M, Ham T, McKenna MJ, McCulloch W, Dalton M, Reed GA, Jensen RA, Baltezor MJ, Anant S, Taylor JA 3rd. Preclinical Pharmacokinetics of Fosciclopirox, a Novel Treatment of Urothelial Cancers, in Rats and Dogs. J Pharmacol Exp Ther. 2019 Aug;370(2):148-159. DOI:10.1124/jpet.119.257972 |
| | Fosciclopirox Preparation Products And Raw materials |
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