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| | Ethanone, 1-(2,5-dimethyl-4-oxazolyl)- (9CI) Basic information |
| | Ethanone, 1-(2,5-dimethyl-4-oxazolyl)- (9CI) Chemical Properties |
| Melting point | 49 °C | | Boiling point | 93 °C(Press: 30 Torr) | | density | 1.074±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 0.11±0.10(Predicted) | | Appearance | White to light yellow Solid |
| | Ethanone, 1-(2,5-dimethyl-4-oxazolyl)- (9CI) Usage And Synthesis |
| Synthesis | The general procedure for the synthesis of 1-(2,5-dimethyl-4-oxazolyl)vinyl ketone, using the compound (CAS: 940879-48-1) as starting material, was as follows: first, 1-(2,5-dimethyloxazol-4-yl)ethanol (1.2 g, 8.50 mmol) was mixed with MnO2 (3.70 g, 42.5 mmol) in chloroform (85 mL). Subsequently, the reaction mixture was heated and stirred at 75 °C for 12 hours. Upon completion of the reaction, it was filtered through a diatomaceous earth pad to remove solid impurities. The filtrate was concentrated under reduced pressure to afford 1-(2,5-dimethyloxazol-4-yl)ethanone (750 mg, 5.39 mmol, 63.4% yield), the product was a light yellow oil, which solidified to a solid on standing. The NMR hydrogen spectrum (500 MHz, CDCl3) data of the product were as follows: δ 2.59 (s, 3H), 2.52 (s, 3H), 2.46 (s, 3H). | | References | [1] Patent: WO2014/98831, 2014, A1. Location in patent: Page/Page column 56 |
| | Ethanone, 1-(2,5-dimethyl-4-oxazolyl)- (9CI) Preparation Products And Raw materials |
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