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| | 2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)- Basic information |
| Product Name: | 2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)- | | Synonyms: | 2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)-;QW24 | | CAS: | 2416312-06-4 | | MF: | C27H28N2O4 | | MW: | 444.52 | | EINECS: | | | Product Categories: | | | Mol File: | 2416312-06-4.mol |  |
| | 2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)- Chemical Properties |
| Boiling point | 544.7±50.0 °C(Predicted) | | density | 1.24±0.1 g/cm3(Predicted) | | pka | 12.95±0.70(Predicted) |
| | 2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)- Usage And Synthesis |
| Uses | QW24 exerts potent anti-tumor activity by down-regulating BMI-1 and is used as an effective therapeutic agent for clinical colorectal cancer research. | | References | [1] Wang J, et al. A novel BMI-1 inhibitor QW24 for the treatment of stem-like colorectal cancer. J Exp Clin Cancer Res. 2019 Oct 22;38(1):422. DOI:10.1186/s13046-019-1392-8 |
| | 2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)- Preparation Products And Raw materials |
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Tag:2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)-(2416312-06-4)
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