2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)-

2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)- Basic information
Product Name:2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)-
Synonyms:2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)-;QW24
CAS:2416312-06-4
MF:C27H28N2O4
MW:444.52
EINECS:
Product Categories:
Mol File:2416312-06-4.mol
2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)- Structure
2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)- Chemical Properties
Boiling point 544.7±50.0 °C(Predicted)
density 1.24±0.1 g/cm3(Predicted)
pka12.95±0.70(Predicted)
Safety Information
MSDS Information
2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)- Usage And Synthesis
UsesQW24 exerts potent anti-tumor activity by down-regulating BMI-1 and is used as an effective therapeutic agent for clinical colorectal cancer research.
References[1] Wang J, et al. A novel BMI-1 inhibitor QW24 for the treatment of stem-like colorectal cancer. J Exp Clin Cancer Res. 2019 Oct 22;38(1):422. DOI:10.1186/s13046-019-1392-8
2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)- Preparation Products And Raw materials
Tag:2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)-(2416312-06-4) Related Product Information
2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-N-(4-methoxyphenyl)-4b,8,8-trimethyl-7-oxo-, (4bS)- 2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-4b,8,8-trimethyl-7-oxo-N-[3-(trifluoromethoxy)phenyl]-, (4bS)- PTC-209 (PTC209 1,6,7-Trihydroxyxanthone PTC-028 5-fluoro-2-(6-fluoro-2-methyl-1H-benzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrimidine-4,6-diamine