2'-DEOXYGUANOSINE 5'-TRIPHOSPHATE DILITHIUM SALT

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2'-DEOXYGUANOSINE 5'-TRIPHOSPHATE DILITHIUM SALT Basic information
Product Name:2'-DEOXYGUANOSINE 5'-TRIPHOSPHATE DILITHIUM SALT
Synonyms:Guanosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-, dilithium salt;2''-Deoxy-5''-guanosine-(tetrahydrogen triphosphate) dilithium salt;2'-DEOXYGUANOSINE 5'-TRIPHOSPHATE DILITHIUM SALT;DGTP-LI2;(2R,3S,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-2-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]oxolan-3-olate
CAS:95648-75-2
MF:C10H17LiN5O13P3
MW:515.13
EINECS:306-016-7
Product Categories:
Mol File:95648-75-2.mol
2'-DEOXYGUANOSINE 5'-TRIPHOSPHATE DILITHIUM SALT Structure
2'-DEOXYGUANOSINE 5'-TRIPHOSPHATE DILITHIUM SALT Chemical Properties
storage temp. −20°C
Safety Information
Safety Statements 22-24/25
WGK Germany 3
F 10-21
MSDS Information
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SigmaAldrich English
2'-DEOXYGUANOSINE 5'-TRIPHOSPHATE DILITHIUM SALT Usage And Synthesis
UsesdGTP-15N5 (2'-Deoxyguanosine-5'-triphosphate-15N5) dilithium is 15N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
References[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Kapoor I, et al. Nucleoside Diphosphate Kinase Escalates A-to-C Mutations in MutT-Deficient Strains of Escherichia coli. J Bacteriol. 2019;202(1):e00567-19. Published 2019 Dec 6. DOI:10.1128/JB.00567-19
2'-DEOXYGUANOSINE 5'-TRIPHOSPHATE DILITHIUM SALT Preparation Products And Raw materials
Tag:2'-DEOXYGUANOSINE 5'-TRIPHOSPHATE DILITHIUM SALT(95648-75-2) Related Product Information
Desciclovir 6H-Purin-6-one, 1,9-dihydro-9-methyl- (9CI) 9-ETHYLGUANINE 2-AMINO-9-(BETA-D-2-DEOXYRIBOFURANOSYL)PURINE dilithium dihydrogen diphosphate 9-METHYLGUANINE 2'-DEOXYGUANOSINE 5'-TRIPHOSPHATE DILITHIUM SALT