Benzeneacetamide, N-methyl-4-(1,8-naphthyridin-2-yl)-

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Benzeneacetamide, N-methyl-4-(1,8-naphthyridin-2-yl)- manufacturers
Benzeneacetamide, N-methyl-4-(1,8-naphthyridin-2-yl)- Basic information
Product Name:Benzeneacetamide, N-methyl-4-(1,8-naphthyridin-2-yl)-
Synonyms:Benzeneacetamide, N-methyl-4-(1,8-naphthyridin-2-yl)-;Succinate/succinate receptor antagonist 1;2-(4-(1,8-naphthyridin-2-yl)phenyl)-N-methylacetamide;Succinate/succinate receptor antagonist 1, 10 mM in DMSO
CAS:2361972-29-2
MF:C17H15N3O
MW:277.33
EINECS:
Product Categories:
Mol File:2361972-29-2.mol
Benzeneacetamide, N-methyl-4-(1,8-naphthyridin-2-yl)- Structure
Benzeneacetamide, N-methyl-4-(1,8-naphthyridin-2-yl)- Chemical Properties
Boiling point 546.5±50.0 °C(Predicted)
density 1.202±0.06 g/cm3(Predicted)
pka15.73±0.46(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
Benzeneacetamide, N-methyl-4-(1,8-naphthyridin-2-yl)- Usage And Synthesis
UsesSuccinate/succinate receptor antagonist 1 (compound 7a) is a succinate/succinate receptor antagonist. Succinate/succinate receptor antagonist 1 blocks succinate signaling in gingival tissue. Succinate/succinate receptor antagonist 1 inhibits the activation of succinate receptor 1 (SucnRl) with an IC50 value of 20 μΜ. Succinate/succinate receptor antagonist 1 can be used for the research of periodontal disease[1].
References[1] LI, Xin, et al. PERIODONTAL DISEASE THERAPY. WO2019136022. 2020.
Benzeneacetamide, N-methyl-4-(1,8-naphthyridin-2-yl)- Preparation Products And Raw materials
Tag:Benzeneacetamide, N-methyl-4-(1,8-naphthyridin-2-yl)-(2361972-29-2) Related Product Information
Benzeneacetamide, N-methyl-4-(1,8-naphthyridin-2-yl)- Immunology/Inflammation Compound Library NF-56-EJ40 cis-Epoxysuccinic acid SUCNR1-IN-2 1-[2-Hydroxy-4-methoxy-5-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one