1-Azetidinecarbonitrile, 3-([1,1'-biphenyl]-4-ylmethoxy)- manufacturers
- NAAA-IN-3
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- $2500.00
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2026-04-20
- CAS:1831115-59-3
- Purity:
- Supply Ability: 10g
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| | 1-Azetidinecarbonitrile, 3-([1,1'-biphenyl]-4-ylmethoxy)- Basic information |
| | 1-Azetidinecarbonitrile, 3-([1,1'-biphenyl]-4-ylmethoxy)- Chemical Properties |
| Boiling point | 469.2±45.0 °C(Predicted) | | density | 1.20±0.1 g/cm3(Predicted) | | pka | -5.92±0.40(Predicted) |
| | 1-Azetidinecarbonitrile, 3-([1,1'-biphenyl]-4-ylmethoxy)- Usage And Synthesis |
| Uses | NAAA-IN-3 (Compound 17a) is a potent and selective inhibitor of NAAA with an IC50 of 50 nM. NAAA is a cysteine amidase which preferentially hydrolyzes the endogenous biolipids palmitoylethanolamide (PEA) and oleoylethanolamide (OEA). NAAA-IN-3 has the potential for the research of inflammation and pain[1]. | | References | [1] Malamas MS, et al. Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors. Bioorg Med Chem. 2020 Jan 1;28(1):115195. DOI:10.1016/j.bmc.2019.115195 |
| | 1-Azetidinecarbonitrile, 3-([1,1'-biphenyl]-4-ylmethoxy)- Preparation Products And Raw materials |
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