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TargetMol
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Product Name:Formycin triphosphate
CAS:16409-13-5
Package:50mg;10mg
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| Company Name: |
CHEMICAL LAND21
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| Tel: |
82- 2 -783 - 8063 |
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sales21@chemicalland21.com |
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| | formycin triphosphate Basic information |
| Product Name: | formycin triphosphate | | Synonyms: | formycin triphosphate;D-Ribitol, 1-C-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-, 5-(tetrahydrogen triphosphate), (1S)- | | CAS: | 16409-13-5 | | MF: | C10H16N5O13P3 | | MW: | 507.18 | | EINECS: | | | Product Categories: | | | Mol File: | 16409-13-5.mol |  |
| | formycin triphosphate Chemical Properties |
| Boiling point | 977.3±75.0 °C(Predicted) | | density | 2.158±0.06 g/cm3(Predicted) | | pka | 0.97±0.50(Predicted) |
| | formycin triphosphate Usage And Synthesis |
| Uses | Formycin triphosphate is a fluorescent analogue of ATP which on binding to enzyme active sites exhibits enhanced fluorescence. Formycin triphosphate is an ATP-competitive chicken liver pyruvate carboxylase inhibitor. Formycin triphosphate potentiates atrial natriuretic factor (ANF)-stimulated guanylate cyclase activity with an EC50 at about 90 μM and inhibits ATP-stimulated guanylate cyclase activity with an IC50 at about 100 μM[1][2]. | | References | [1] P V Attwood, et al. Interaction of formycin A-5'-triphosphate with pyruvate carboxylase. FEBS Lett. 1984 Sep 17;175(1):45-50. DOI:10.1016/0014-5793(84)80566-9
[2] C H Chang, et al. Formycin triphosphate as a probe for the ATP binding site involved in the activation of guanylate cyclase. Eur J Pharmacol. 1992 Oct 1;227(2):229-31. DOI:10.1016/0922-4106(92)90133-g |
| | formycin triphosphate Preparation Products And Raw materials |
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