Methanesulfonamide, N-[1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-oxospiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]-

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Methanesulfonamide, N-[1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-oxospiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]- Suppliers list
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Methanesulfonamide, N-[1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-oxospiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]- manufacturers
Methanesulfonamide, N-[1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-oxospiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]- Basic information
Product Name:Methanesulfonamide, N-[1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-oxospiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]-
Synonyms:Methanesulfonamide, N-[1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-oxospiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]-;Antiarrhythmic agent-1
CAS:136081-07-7
MF:C25H27N3O4S
MW:465.56
EINECS:
Product Categories:
Mol File:136081-07-7.mol
Methanesulfonamide, N-[1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-oxospiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]- Structure
Methanesulfonamide, N-[1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-oxospiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]- Chemical Properties
Boiling point 674.5±65.0 °C(Predicted)
density 1.39±0.1 g/cm3(Predicted)
pka7.59±0.20(Predicted)
Safety Information
MSDS Information
Methanesulfonamide, N-[1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-oxospiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]- Usage And Synthesis
UsesAntiarrhythmic agent-1 (example I) is an antiarrhythmic agent and an IKr potassium channel blocker (IC50<1 μM)[1].
References[1] Slaughter DE, et al. Preparation of N-[1'-(6-cyano-4-hydroxy-1,2,3,4-tetrahydro-2(R)-naphthalenyl-3,4-dihydro-4(R)-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin-6-yl]methanesulfonamide as an antiarrhythmic agent.. World Intellectual Property Organization, WO9607411A1.1996-03-14.
Methanesulfonamide, N-[1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-oxospiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]- Preparation Products And Raw materials
Tag:Methanesulfonamide, N-[1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-oxospiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]-(136081-07-7) Related Product Information
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