4-[(Hydroxyamino)carbonyl]-N-2-naphthalenylbenzeneacetamide

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4-[(Hydroxyamino)carbonyl]-N-2-naphthalenylbenzeneacetamide manufacturers

  • HDAC6-IN-9
  • HDAC6-IN-9 pictures
  • $176.00
  • 2026-07-14
  • CAS:2796282-58-9
  • Purity: 98.87%
  • Supply Ability: 10g
4-[(Hydroxyamino)carbonyl]-N-2-naphthalenylbenzeneacetamide Basic information
Product Name:4-[(Hydroxyamino)carbonyl]-N-2-naphthalenylbenzeneacetamide
Synonyms:4-[(Hydroxyamino)carbonyl]-N-2-naphthalenylbenzeneacetamide
CAS:2796282-58-9
MF:C19H16N2O3
MW:320.34
EINECS:
Product Categories:
Mol File:2796282-58-9.mol
4-[(Hydroxyamino)carbonyl]-N-2-naphthalenylbenzeneacetamide Structure
4-[(Hydroxyamino)carbonyl]-N-2-naphthalenylbenzeneacetamide Chemical Properties
density 1.342±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
pka8.88±0.10(Predicted)
Safety Information
MSDS Information
4-[(Hydroxyamino)carbonyl]-N-2-naphthalenylbenzeneacetamide Usage And Synthesis
UsesHDAC6-IN-9 (compound 12c) is a potent and selective HDAC6 inhibitor with IC50 values of 11.8, 15.2, 4.2, 139.6, 21.3 nM for HDAC1,HDAC3, HDAC6, HDAC8, HDAC10, respectively. HDAC6-IN-9 shows anti-proliferative activities[1].
IC 50HDAC1: 11.8 nM (IC50); HDAC3: 15.2 nM (IC50); HDAC6: 4.2 nM (IC50); HDAC8: 139.6 nM (IC50); HDAC10: 21.3 nM (IC50)
References[1] Li X,et al. Design, Synthesis, and biological evaluation of HDAC6 inhibitors based on Cap modification strategy. Bioorg Chem. 2022 Aug;125:105874. DOI:10.1016/j.bioorg.2022.105874
4-[(Hydroxyamino)carbonyl]-N-2-naphthalenylbenzeneacetamide Preparation Products And Raw materials
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