| Company Name: |
Fuan Bio |
| Tel: |
15002819872 |
| Email: |
2845971812@qq.com |
|
| Product Name: | 85548e | | Synonyms: | 85548e;U 85548e;U85548e;U-85548e;L-Valine, L-valyl-L-seryl-L-glutaminyl-L-asparaginyl-(2S,4S,5S)-5-amino-4-hydroxy-7-methyl-2-(1-methylethyl)octanoyl-L-isoleucyl- | | CAS: | 124020-62-8 | | MF: | C40H73N9O12 | | MW: | 872.08 | | EINECS: | | | Product Categories: | | | Mol File: | 124020-62-8.mol |  |
| | 85548e Chemical Properties |
| Boiling point | 1280.9±65.0 °C(Predicted) | | density | 1.203±0.06 g/cm3(Predicted) | | pka | 3.38±0.10(Predicted) |
| | 85548e Usage And Synthesis |
| Uses | U-85548E is an HIV protease inhibitor with nanomolar affinity for HIV-1 aspartic protease. By studying its structure-activity relationship, a potent nanomolar inhibitor with inhibitory effects on both HIV-1 and HIV-2 proteases was designed, and its binding mode was studied by X-ray crystallography and molecular modeling. | | References | [1] HIV protease (HIV PR) inhibitor structure‐activity‐selectivity, and active site molecular modeling of high affinity Leu [CH(OH)CH2]Val modified viral and nonviral… |
| | 85548e Preparation Products And Raw materials |
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