Methyl (6S)-4-[4′-[[[[4-[[(3-cyano-4-methyl-1H-indol-7-yl)amino]sulfonyl]phenyl]methyl]amino]carbonyl][1,1′-biphenyl]-4-yl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetate

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Methyl (6S)-4-[4′-[[[[4-[[(3-cyano-4-methyl-1H-indol-7-yl)amino]sulfonyl]phenyl]methyl]amino]carbonyl][1,1′-biphenyl]-4-yl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetate Suppliers list
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Methyl (6S)-4-[4′-[[[[4-[[(3-cyano-4-methyl-1H-indol-7-yl)amino]sulfonyl]phenyl]methyl]amino]carbonyl][1,1′-biphenyl]-4-yl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetate Basic information
Product Name:Methyl (6S)-4-[4′-[[[[4-[[(3-cyano-4-methyl-1H-indol-7-yl)amino]sulfonyl]phenyl]methyl]amino]carbonyl][1,1′-biphenyl]-4-yl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetate
Synonyms:Methyl (6S)-4-[4′-[[[[4-[[(3-cyano-4-methyl-1H-indol-7-yl)amino]sulfonyl]phenyl]methyl]amino]carbonyl][1,1′-biphenyl]-4-yl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetate;PROTAC BRD4 Degrader-19;6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-[4′-[[[[4-[[(3-cyano-4-methyl-1H-indol-7-yl)amino]sulfonyl]phenyl]methyl]amino]carbonyl][1,1′-biphenyl]-4-yl]-2,3,9-trimethyl-, methyl ester, (6S)-;PROTAC BRD42/BRD4 Degrader-19
CAS:2684292-71-3
MF:C44H38N8O5S2
MW:822.96
EINECS:
Product Categories:PROTACs-Please select
Mol File:2684292-71-3.mol
Methyl (6S)-4-[4′-[[[[4-[[(3-cyano-4-methyl-1H-indol-7-yl)amino]sulfonyl]phenyl]methyl]amino]carbonyl][1,1′-biphenyl]-4-yl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetate Structure
Methyl (6S)-4-[4′-[[[[4-[[(3-cyano-4-methyl-1H-indol-7-yl)amino]sulfonyl]phenyl]methyl]amino]carbonyl][1,1′-biphenyl]-4-yl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetate Chemical Properties
density 1.42±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
pka8.66±0.30(Predicted)
form Solid
color White to yellow
Safety Information
MSDS Information
Methyl (6S)-4-[4′-[[[[4-[[(3-cyano-4-methyl-1H-indol-7-yl)amino]sulfonyl]phenyl]methyl]amino]carbonyl][1,1′-biphenyl]-4-yl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetate Usage And Synthesis
UsesPROTAC BRD4 Degrader-19 (compound 176) is a PROTAC that targets BRD4 protein for degradation. PROTAC BRD4 Degrader-19 can be used in cancer research[1].
References[1] Ohba Kiyomi, et al. Medicine containing BRD4 protein degradation inducer. JP2023024381.
Methyl (6S)-4-[4′-[[[[4-[[(3-cyano-4-methyl-1H-indol-7-yl)amino]sulfonyl]phenyl]methyl]amino]carbonyl][1,1′-biphenyl]-4-yl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetate Preparation Products And Raw materials
Tag:Methyl (6S)-4-[4′-[[[[4-[[(3-cyano-4-methyl-1H-indol-7-yl)amino]sulfonyl]phenyl]methyl]amino]carbonyl][1,1′-biphenyl]-4-yl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetate(2684292-71-3) Related Product Information
Methyl (6S)-4-[4′-[[[[4-[[(3-cyano-4-methyl-1H-indol-7-yl)amino]sulfonyl]phenyl]methyl]amino]carbonyl][1,1′-biphenyl]-4-yl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetate Thalidomide Anti-cancer compound library ARV-825 CC-885 CC-90009